Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.43 |
| ▸ | PREP | P48147 | 1/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.37 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28056504 | 0.89 | DPP4 (0.46) | DPP4PREP | |
| SCHEMBL5140895 | 0.87 | DPP4 (0.47) | DPP4PREP | |
| SCHEMBL28834183 | 0.85 | DPP4 (0.48) | DPP4 | |
| SCHEMBL15238182 | 0.83 | — | — | |
| SCHEMBL2605419 | 0.83 | — | — | |
| SCHEMBL9661620 | 0.80 | LMNA (0.34) | DPP4 | |
| SCHEMBL2744920 | 0.80 | PREP (0.37) | DPP4PREPDPP8DPP9 | |
| SCHEMBL2605420 | 0.78 | DPP4 (0.42) | DPP4PREPDPP8DPP9 | |
| SCHEMBL4434550 | 0.75 | — | — | |
| SCHEMBL23598744 | 0.74 | DPP4 (0.43) | DPP4PREPDPP8DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3650447-A1 | NEW SELECTIVE MODULATORS OF INSECT NICOTINIC ACETYLCHOLINE RECEPTORS | Universite de Nantes (FR) | 2020-05-13 | — | — | EP | disclosed |