Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | METAP2 | P50579 | 4/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | TTK | P33981 | 1/20 | 0.35 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2805532 | 0.86 | PRKAA2 (0.40) | CYP3A4CYP2C9CYP2C19ALDH1A1LMNA | |
| SCHEMBL13128434 | 0.85 | BDKRB1 (0.47) | ALDH1A1LMNALRRK2NAMPTPRKAA2 | |
| SCHEMBL2804886 | 0.84 | AKT2 (0.39) | ALDH1A1METAP2POLBRAB9ALRRK2 | |
| SCHEMBL14857219 | 0.83 | CHRM4 (0.36) | CYP3A4CYP2C9CYP2C19ALDH1A1LMNA | |
| SCHEMBL184742 | 0.82 | CYP3A4 (0.40) | CYP3A4CYP2C9CYP2C19ALDH1A1LMNA | |
| SCHEMBL2792629 | 0.82 | METAP2 (0.39) | ALDH1A1METAP2POLBRAB9ALRRK2 | |
| SCHEMBL2806168 | 0.82 | PRKAA2 (0.39) | LRRK2PRKAA2 | |
| SCHEMBL2805701 | 0.82 | BDKRB1 (0.41) | CHRM4PRKAA2 | |
| Trifluoroacetic Acid SCHEMBL2805210 | 0.81 | AKT2 (0.36) | METAP2POLBRAB9ALRRK2NPC1 | |
| SCHEMBL200841 | 0.80 | CHRM4 (0.35) | ALDH1A1LMNALRRK2TTKCHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100240669-A1 | NEW COMPOUNDS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100240669-A1 | NEW COMPOUNDS | ADORA1, H1-10, P2RY11 | CYP3A4 467/4885CYP2C9 68/4885CYP2C19 136/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.