Nitrogen

Nitrogen

SCHEMBL28056541

Cc1ccccc1Oc1ccccc1C.N#N

nearest known ligand 0.67

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.60
SMN1; SMN2 Q16637 2/20 0.60
MEN1 O00255 2/20 0.60
KMT2A Q03164 2/20 0.60
NPC1 O15118 1/20 0.60
RAB9A P51151 1/20 0.60
AR P10275 5/20 0.52
ACHE P22303 1/20 0.47
SLC6A2 P23975 2/20 0.43
SLC6A4 P31645 2/20 0.43
SLC6A3 Q01959 2/20 0.43
ALDH1A1 P00352 2/20 0.43
CYP1A2 P05177 2/20 0.43
HPGD P15428 2/20 0.43
CYP2C19 P33261 2/20 0.43
LMNA P02545 1/20 0.43
CYP2C9 P11712 1/20 0.43
GLA P06280 1/20 0.42
MRGPRX1 Q96LB2 1/20 0.42
CA12 O43570 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29637724 0.94 TSHR (0.65) TSHRSMN1; SMN2MEN1KMT2ANPC1
SCHEMBL127000 0.94 TSHR (0.65) TSHRSMN1; SMN2MEN1KMT2ANPC1
Phosphine SCHEMBL22634020 0.92 TSHR (0.62) TSHRSMN1; SMN2MEN1KMT2ANPC1
Fluoride SCHEMBL27757467 0.92 TSHR (0.62) TSHRSMN1; SMN2MEN1KMT2ANPC1
Propane SCHEMBL28061941 0.86 TSHR (0.58) TSHRSMN1; SMN2MEN1KMT2ANPC1
Formaldehyde SCHEMBL9868053 0.86 SMN1; SMN2 (0.58) TSHRSMN1; SMN2MEN1KMT2ANPC1
SCHEMBL29185416 0.84 TSHR (0.56) TSHRSMN1; SMN2MEN1KMT2ANPC1
Biphenyl SCHEMBL7781908 0.84 SMN1; SMN2 (0.56) TSHRSMN1; SMN2MEN1KMT2ANPC1
SCHEMBL8486101 0.82 MEN1 (0.54) TSHRSMN1; SMN2MEN1KMT2ANPC1
Ethylene Glycol SCHEMBL2467929 0.82 TSHR (0.54) TSHRSMN1; SMN2MEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105295423-A Weak acid violet-red dye and preparation method thereof ZHEJIANG JINHUA HANLLYCOME CHEMICAL CO LTD 2016-02-03 CN claimed
CN-105295423-A Weak acid violet-red dye and preparation method thereof ZHEJIANG JINHUA HANLLYCOME CHEMICAL CO LTD 2016-02-03 CN disclosed