Biphenyl

Biphenyl

SCHEMBL7781908

Cc1ccccc1Oc1ccccc1C.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 4/20 0.56
TSHR P16473 4/20 0.56
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
NPC1 O15118 2/20 0.56
RAB9A P51151 2/20 0.56
ALDH1A1 P00352 4/20 0.50
MAPT P10636 3/20 0.45
CYP1A2 P05177 2/20 0.45
CYP2C9 P11712 2/20 0.45
HPGD P15428 2/20 0.45
CYP2C19 P33261 2/20 0.45
KDM4E B2RXH2 1/20 0.45
GAA P10253 1/20 0.45
MCHR1 Q99705 1/20 0.45
AR P10275 2/20 0.44
ACHE P22303 1/20 0.43
POLB P06746 1/20 0.42
SCN4A P35499 1/20 0.41
SLC6A2 P23975 2/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL127000 0.89 TSHR (0.65) SMN1; SMN2TSHRMEN1KMT2ANPC1
SCHEMBL29637724 0.89 TSHR (0.65) SMN1; SMN2TSHRMEN1KMT2ANPC1
Fluoride SCHEMBL27757467 0.87 TSHR (0.62) SMN1; SMN2TSHRMEN1KMT2ANPC1
Phosphine SCHEMBL22634020 0.87 TSHR (0.62) SMN1; SMN2TSHRMEN1KMT2ANPC1
SCHEMBL9859720 0.87 NCOA1 (0.52) SMN1; SMN2TSHRMEN1KMT2ANPC1
SCHEMBL27618811 0.87 ALDH1A1 (0.60) SMN1; SMN2TSHRMEN1KMT2ANPC1
Nitrogen SCHEMBL28056541 0.84 TSHR (0.60) SMN1; SMN2TSHRMEN1KMT2ANPC1
Formaldehyde SCHEMBL9868053 0.82 SMN1; SMN2 (0.58) SMN1; SMN2TSHRMEN1KMT2ANPC1
Propane SCHEMBL28061941 0.82 TSHR (0.58) SMN1; SMN2TSHRMEN1KMT2ANPC1
SCHEMBL11585109 0.81 ALDH1A1 (0.52) SMN1; SMN2TSHRMEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1140515-A1 HEAT SENSITIVE RECORDING MATERIAL Ciba SC Holding AG (CH) 2001-10-10 EP claimed
WO-2000035679-A1 HEAT SENSITIVE RECORDING MATERIAL CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2000-06-22 WO claimed