Formaldehyde

Formaldehyde

SCHEMBL9868053

C=O.Cc1ccccc1Oc1ccccc1C

nearest known ligand 0.64

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 3/20 0.58
TSHR P16473 2/20 0.58
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
NPC1 O15118 1/20 0.58
RAB9A P51151 1/20 0.58
AR P10275 4/20 0.46
LMNA P02545 1/20 0.46
ACHE P22303 1/20 0.45
HPGD P15428 2/20 0.44
SLC6A2 P23975 2/20 0.42
SLC6A4 P31645 2/20 0.42
SLC6A3 Q01959 2/20 0.42
ALDH1A1 P00352 2/20 0.42
CYP1A2 P05177 2/20 0.42
CYP2C19 P33261 2/20 0.42
CYP2C9 P11712 1/20 0.42
PTGS2 P35354 1/20 0.41
GLA P06280 1/20 0.41
MRGPRX1 Q96LB2 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL127000 0.92 TSHR (0.65) SMN1; SMN2TSHRMEN1KMT2ANPC1
SCHEMBL29637724 0.92 TSHR (0.65) SMN1; SMN2TSHRMEN1KMT2ANPC1
Phosphine SCHEMBL22634020 0.89 TSHR (0.62) SMN1; SMN2TSHRMEN1KMT2ANPC1
Fluoride SCHEMBL27757467 0.89 TSHR (0.62) SMN1; SMN2TSHRMEN1KMT2ANPC1
Nitrogen SCHEMBL28056541 0.86 TSHR (0.60) SMN1; SMN2TSHRMEN1KMT2ANPC1
Propane SCHEMBL28061941 0.84 TSHR (0.58) SMN1; SMN2TSHRMEN1KMT2ANPC1
SCHEMBL9070304 0.83 SMN1; SMN2 (0.52) SMN1; SMN2TSHRMEN1KMT2ANPC1
SCHEMBL5535598 0.83 TSHR (0.52) SMN1; SMN2TSHRMEN1KMT2ANPC1
SCHEMBL29185416 0.82 TSHR (0.56) SMN1; SMN2TSHRMEN1KMT2ANPC1
Biphenyl SCHEMBL7781908 0.82 SMN1; SMN2 (0.56) SMN1; SMN2TSHRMEN1KMT2ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5030670-A Stable aqueous dispersions of tetraalkylpiperidines SANDOZ LTD. (CH) 1991-07-09 US claimed
US-4780494-A Stable aqueous dispersions of tetraalkylpiperidines SANDOZ LTD. (CH) 1988-10-25 US claimed
US-5030670-A Stable aqueous dispersions of tetraalkylpiperidines SANDOZ LTD. (CH) 1991-07-09 US disclosed
EP-0306791-A1 Self-levelling mortar mixture BAYER AG (DE) 1989-03-15 EP disclosed
US-4780494-A Stable aqueous dispersions of tetraalkylpiperidines SANDOZ LTD. (CH) 1988-10-25 US disclosed