Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28056958 | 0.83 | MGLL (0.41) | ALDH1A1MAPTKDM4ERAB9ANPC1 | |
| SCHEMBL28056948 | 0.82 | NPC1 (0.40) | ALDH1A1MAPK1KDM4ERAB9ANPC1 | |
| SCHEMBL28056873 | 0.82 | MAPT (0.52) | MAPTHTTRAB9ANPC1LMNA | |
| SCHEMBL28056871 | 0.80 | EPHX1 (0.35) | ALDH1A1KDM4EGAALMNAKMT2A | |
| SCHEMBL28826651 | 0.79 | ABAT (0.35) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL28056959 | 0.72 | KDM4E (0.41) | ALDH1A1MAPTKDM4EGAARAB9A | |
| SCHEMBL27977584 | 0.70 | ALDH1A1 (0.44) | ALDH1A1MAPTMAPK1KDM4EGAA | |
| SCHEMBL2980631 | 0.69 | MAPT (0.58) | ALDH1A1MAPTMAPK1GAAHTT | |
| SCHEMBL10593979 | 0.69 | MAPT (0.40) | ALDH1A1MAPTKDM4EGAARAB9A | |
| SCHEMBL31319084 | 0.68 | ALDH1A1 (0.39) | ALDH1A1MAPK1RAB9ANPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103992265-B | Two three bromo 1,3-bis-pyridine alkali propane and preparation method thereof, using method, recovery method and application | XI'AN JIAOTONG UNIVERSITY (CN) | 2016-02-24 | — | — | CN | disclosed |