Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 3/20 | 0.43 |
| ▸ | KLKB1 | P03952 | 8/20 | 0.37 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.36 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.36 |
| ▸ | MAP4K1 | Q92918 | 3/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.33 |
| ▸ | HTR6 | P50406 | 1/20 | 0.33 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | HTR3A | P46098 | 1/20 | 0.33 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9814928 | 0.78 | FAAH (0.43) | FAAHPDGFRBPDGFRAKDRHTR3A | |
| SCHEMBL24338030 | 0.78 | FAAH (0.45) | FAAHKLKB1MAP4K1PDGFRBPDGFRA | |
| SCHEMBL27466882 | 0.78 | CYP1A2 (0.47) | FAAHPDGFRBPDGFRA | |
| SCHEMBL28158715 | 0.77 | FAAH (0.42) | FAAHKLKB1MAP4K1MET | |
| SCHEMBL8099185 | 0.74 | PDE10A (0.43) | FAAHKLKB1PDGFRBPDGFRAMET | |
| SCHEMBL27960121 | 0.74 | PDGFRB (0.30) | PDGFRBPDGFRA | |
| SCHEMBL28158830 | 0.73 | MAOB (0.43) | FAAHKLKB1MAP4K1 | |
| SCHEMBL3604906 | 0.71 | TDP1 (0.46) | FAAHPDE3BPDE3APDGFRBPDGFRA | |
| SCHEMBL8299460 | 0.71 | MAPT (0.51) | FAAH | |
| SCHEMBL17442812 | 0.69 | KLKB1 (0.42) | KLKB1MAP4K1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103153063-B | Quinoline derivatives and melk inhibitors containing the same | ONCOTHERAPY SCIENCE, INC. (JP) | 2016-02-17 | — | — | CN | disclosed |