Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.41 |
| ▸ | HTR3A | P46098 | 1/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.36 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12507578 | 0.86 | PDGFRB (0.50) | MAPTHRH4PARP1KMT2AFGFR3 | |
| SCHEMBL22276493 | 0.86 | CYP1A2 (0.41) | KMT2ANPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL16541640 | 0.85 | NPC1 (0.49) | MAPTPARP1PDE10AKMT2ANPC1 | |
| SCHEMBL24338030 | 0.82 | FAAH (0.45) | FAAHKMT2APDGFRBPDGFRA | |
| SCHEMBL8099185 | 0.81 | PDE10A (0.43) | FAAHHRH4HTR3APDE10AKDR | |
| SCHEMBL28158715 | 0.81 | FAAH (0.42) | FAAHMAPTPDE10A | |
| SCHEMBL6058477 | 0.80 | ALDH1A1 (0.47) | MAPTPARP1PDE10AKMT2ANPC1 | |
| SCHEMBL9334190 | 0.79 | PDE10A (0.55) | MAPTPARP1PDE10AKMT2ANPC1 | |
| SCHEMBL18562139 | 0.79 | CYP1A2 (0.40) | PARP1PDE10AKMT2ANPC1RAB9A | |
| SCHEMBL28056993 | 0.78 | FAAH (0.43) | FAAHHRH4HTR3AKDRPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10479770-B2 | Phosphatidylinositol 3-kinase inhibitors | GILEAD SCIENCES, INC. (US) | 2019-11-19 | — | — | US | disclosed |
| US-20180086719-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | GILEAD SCIENCES, INC. | 2018-03-29 | — | — | US | disclosed |
| CN-101277696-B | Quinoline derivatives as antibacterial agents | JANSSEN PHARMACEUTICA N.V. (BE) | 2015-09-02 | — | — | CN | disclosed |
| EP-0247277-B1 | PROCESS FOR THE PREPARATION OF 5-ALKYLQUINOLINIC ACIDS AND MEANS FOR CARRYING OUT THIS PROCESS | RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1991-09-11 | — | — | EP | disclosed |
| EP-0247277-A2 | Process for the preparation of 5-alkylquinolinic acids and means for carrying out this process | RÜTGERSWERKE AKTIENGESELLSCHAFT (DE) | 1987-12-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180086719-A1 | PHOSPHATIDYLINOSITOL 3-KINASE INHIBITORS | PIK3CA, AKT3, PI4KA | FAAH 4744/4885MAPT 276/4885HRH4 1727/4885 |
| US-10479770-B2 | Phosphatidylinositol 3-kinase inhibitors | PIK3CA, AKT3, PI4KA | FAAH 4744/4885MAPT 276/4885HRH4 1727/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.