Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2331297 | 0.73 | SLC6A3 (0.41) | SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL6138393 | 0.72 | — | — | |
| Hydrochloric Acid SCHEMBL8611493 | 0.72 | SLC6A4 (0.39) | SLC6A4SLC6A3SLC6A2 | |
| Hydrochloric Acid SCHEMBL4698946 | 0.70 | — | — | |
| SCHEMBL9271137 | 0.65 | — | — | |
| SCHEMBL9191228 | 0.64 | — | — | |
| SCHEMBL23089167 | 0.64 | SOS1 (0.31) | — | |
| SCHEMBL17888369 | 0.63 | NPSR1 (0.31) | — | |
| SCHEMBL5009668 | 0.63 | — | — | |
| SCHEMBL23133779 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103153063-B | Quinoline derivatives and melk inhibitors containing the same | ONCOTHERAPY SCIENCE, INC. (JP) | 2016-02-17 | — | — | CN | disclosed |