Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 14/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 14/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 12/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8611493 | 0.97 | SLC6A4 (0.39) | SLC6A3SLC6A4SLC6A2OPRM1 | |
| SCHEMBL6138393 | 0.89 | — | — | |
| Hydrochloric Acid SCHEMBL4698946 | 0.86 | — | — | |
| SCHEMBL17888369 | 0.77 | NPSR1 (0.31) | — | |
| SCHEMBL7501442 | 0.75 | HTR1A (0.34) | SLC6A3SLC6A4SLC6A2OPRM1 | |
| SCHEMBL1994698 | 0.75 | SLC6A4 (0.30) | SLC6A3SLC6A4 | |
| SCHEMBL17888408 | 0.74 | KDM4E (0.38) | — | |
| SCHEMBL23089167 | 0.73 | SOS1 (0.31) | — | |
| SCHEMBL28056995 | 0.73 | SLC6A4 (0.31) | SLC6A3SLC6A4SLC6A2 | |
| Hydrochloric Acid SCHEMBL9177709 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023114823-A1 | BENZOTHIOPHENE DERIVATIVES AS RXFP1 AGONISTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2023-06-22 | — | — | WO | disclosed |
| WO-2022070288-A1 | NITROGEN-CONTAINING BICYCLIC COMPOUND | 旭化成ファーマ株式会社 | 2022-04-07 | — | — | WO | disclosed |
| US-10562878-B2 | Cycloalkylamines as monoamine reuptake inhibitors | SUNOVION PHARAMCEUTICALS INC. (US) | 2020-02-18 | — | — | US | disclosed |
| EP-3504213-A1 | AMINO-PYRROLOPYRIMIDINONE COMPOUNDS AND METHODS OF USE THEREOF | ArQule, Inc. (US) | 2019-07-03 | — | — | EP | disclosed |
| WO-2018039310-A1 | AMINO-PYRROLOPYRIMIDINONE COMPOUNDS AND METHODS OF USE THEREOF | ARQULE, INC. (US) | 2018-03-01 | — | — | WO | disclosed |
| US-9868718-B2 | Cycloalkylamines as monoamine reuptake inhibitors | SUNOVION PHARMACEUTICALS INC. (US) | 2018-01-16 | — | — | US | disclosed |
| US-20150126511-A1 | CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS | SUNOVION PHARMACEUTICALS INC. | 2015-05-07 | — | — | US | disclosed |
| US-8877975-B2 | Cycloalkylamines as monoamine reuptake inhibitors | SUNOVION PHARMACEUTICALS INC. (US) | 2014-11-04 | — | — | US | disclosed |
| EP-2356171-A1 | SILOXANE COPOLYMERS AND METHODS FOR PRODUCTION THEREOF | Wacker Chemie AG (DE) | 2011-08-17 | — | — | EP | disclosed |
| US-20100190861-A1 | CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS | SUNOVION PHARMACEUTICALS INC. | 2010-07-29 | — | — | US | disclosed |
| EP-1885770-A1 | DEFOAMER FORMULATIONS | Wacker Chemie AG (DE) | 2008-02-13 | — | — | EP | disclosed |
| US-7273952-B2 | Substituted C-cyclohexylmethylamine derivatives | GRUENENTHAL GMBH (DE) | 2007-09-25 | — | — | US | disclosed |
| US-20070203111-A1 | Cycloalkylamines as monoamine reuptake inhibitors | SEPRACOR INC. (US) | 2007-08-30 | — | — | US | disclosed |
| EP-1753804-A2 | METHOD FOR MODIFYING FIBROUS SUBSTRATES WITH SILOXANE COPOLYMERS | Wacker Chemie AG (DE) | 2007-02-21 | — | — | EP | disclosed |
| WO-2006128624-A1 | DEFOAMER FORMULATIONS | WACKER CHEMIE AG (DE) | 2006-12-07 | — | — | WO | disclosed |
| US-7022739-B2 | Substituted 1-aminobutan-3-ol compounds | GRUENENTHAL GMBH (DE) | 2006-04-04 | — | — | US | disclosed |
| WO-2005121218-A2 | METHOD FOR MODIFYING FIBROUS SUBSTRATES WITH SILOXANE COPOLYMERS | WACKER CHEMIE AG (DE) | 2005-12-22 | — | — | WO | disclosed |
| EP-1572780-A2 | HYDROPHILIC COPOLYSILOXANES AND METHOD FOR THE PRODUCTION THEREOF | Wacker-Chemie GmbH (DE) | 2005-09-14 | — | — | EP | disclosed |
| WO-2004056907-A2 | HYDROPHILIC COPOLYSILOXANES AND METHOD FOR THE PRODUCTION THEREOF | WACKER-CHEMIE GMBH (DE) | 2004-07-08 | — | — | WO | disclosed |
| WO-2002028816-A1 | SUBSTITUTED 5-AMINO-1-PENTENE-3-OL DERIVATIVES | BUSCHMANN, HELMUT | 2002-04-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150126511-A1 | CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS | SLC18A2, SLC6A2, SLC18A3 | SLC6A3 4/4885SLC6A4 5/4885SLC6A2 2/4885 |
| US-20070203111-A1 | Cycloalkylamines as monoamine reuptake inhibitors | SLC18A2, SLC6A2, SLC18A3 | SLC6A3 4/4885SLC6A4 5/4885SLC6A2 2/4885 |
| US-20100190861-A1 | CYCLOALKYLAMINES AS MONOAMINE REUPTAKE INHIBITORS | SLC18A2, SLC6A2, SLC18A3 | SLC6A3 4/4885SLC6A4 5/4885SLC6A2 2/4885 |
| US-10562878-B2 | Cycloalkylamines as monoamine reuptake inhibitors | SLC18A2, SLC6A2, SLC18A3 | SLC6A3 4/4885SLC6A4 5/4885SLC6A2 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.