Chloroform

Chloroform

SCHEMBL28057528

C=Cc1ccc(C=C)cc1.ClC(Cl)Cl

nearest known ligand 0.73

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.73
TSHR P16473 1/20 0.53
TDP1 Q9NUW8 2/20 0.44
HDAC8 Q9BY41 2/20 0.43
TP53 P04637 1/20 0.35
TAS1R3 Q7RTX0 2/20 0.34
TAS1R1 Q7RTX1 2/20 0.34
TRPA1 O75762 1/20 0.33
CHRNB2 P17787 1/20 0.33
CHRNB4 P30926 1/20 0.33
CHRNA3 P32297 1/20 0.33
CHRNA7 P36544 1/20 0.33
CHRNA4 P43681 1/20 0.33
POLB P06746 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL473081 0.86 ALDH1A1 (1.00) ALDH1A1TSHRTDP1HDAC8TP53
SCHEMBL7639 0.86 ALDH1A1 (1.00) ALDH1A1TSHRTDP1HDAC8TP53
SCHEMBL1264527 0.83 ALDH1A1 (0.58) ALDH1A1TSHRTDP1HDAC8TP53
Water SCHEMBL20378930 0.82 ALDH1A1 (0.92) ALDH1A1TSHRTDP1HDAC8TP53
Water SCHEMBL28759143 0.82 ALDH1A1 (0.92) ALDH1A1TSHRTDP1HDAC8TP53
SCHEMBL29229894 0.82 ALDH1A1 (0.92) ALDH1A1TSHRTDP1HDAC8TP53
Hydrochloric Acid SCHEMBL23581954 0.82 ALDH1A1 (0.92) ALDH1A1TSHRTDP1HDAC8TP53
Ethylene SCHEMBL7955374 0.82 ALDH1A1 (0.92) ALDH1A1TSHRTDP1HDAC8TP53
SCHEMBL6935569 0.82 ALDH1A1 (0.92) ALDH1A1TSHRTDP1HDAC8TP53
SCHEMBL22496003 0.82 ALDH1A1 (0.92) ALDH1A1TSHRTDP1HDAC8TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103623789-B Process multi-functional absorption agent and the preparation method of petrochemical wastewater for enhanced biodegradation BEIJING NORMAL UNIVERSITY (CN) 2016-05-11 CN disclosed