Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP4 | P49662 | 1/20 | 0.50 |
| ▸ | CASP5 | P51878 | 1/20 | 0.50 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | GALR3 | O60755 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11305784 | 0.90 | CASP1 (0.39) | CASP1CASP4CASP5HRH1SMN1; SMN2 | |
| SCHEMBL8899220 | 0.83 | HRH4 (0.54) | CASP1CASP4CASP5SMN1; SMN2USP2 | |
| SCHEMBL2815977 | 0.79 | KMT2A (0.55) | SMN1; SMN2ALDH1A1MAPK1KMT2AHTT | |
| SCHEMBL1975340 | 0.78 | HRH1 (0.70) | CASP1CASP4CASP5HRH1SMN1; SMN2 | |
| SCHEMBL11737861 | 0.78 | HSD17B10 (0.63) | CASP1SMN1; SMN2USP2TDP1ALDH1A1 | |
| SCHEMBL11743038 | 0.76 | HSD17B10 (0.66) | CASP1SMN1; SMN2USP2TDP1ALDH1A1 | |
| SCHEMBL11736253 | 0.76 | HSD17B10 (0.66) | CASP1SMN1; SMN2USP2TDP1ALDH1A1 | |
| SCHEMBL11208162 | 0.75 | SMN1; SMN2 (0.71) | HRH1SMN1; SMN2USP2TDP1ALDH1A1 | |
| SCHEMBL29754406 | 0.75 | CASP1 (0.80) | CASP1CASP4CASP5HRH1SMN1; SMN2 | |
| SCHEMBL1697668 | 0.73 | CASP1 (0.48) | CASP1CASP4CASP5HRH1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |
| WO-2010118367-A2 | ANTIVIRAL PYRIMIDINES | PROGENICS PHARMACEUTICALS, INC. (US) | 2010-10-14 | — | — | WO | disclosed |