Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | INPP5D | Q92835 | 1/20 | 0.61 |
| ▸ | CDC25A | P30304 | 5/20 | 0.55 |
| ▸ | POLA1 | P09884 | 1/20 | 0.54 |
| ▸ | CDC25B | P30305 | 1/20 | 0.54 |
| ▸ | NPC1L1 | Q9UHC9 | 3/20 | 0.53 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | FNTA | P49354 | 2/20 | 0.51 |
| ▸ | FNTB | P49356 | 2/20 | 0.51 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.51 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.51 |
| ▸ | EFNA1 | P20827 | 1/20 | 0.51 |
| ▸ | EPHA2 | P29317 | 1/20 | 0.51 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.51 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15346210 | 0.89 | CYP2D6 (0.62) | CYP2D6CYP2C19INPP5DCDC25APOLA1 | |
| SCHEMBL9664069 | 0.89 | CYP2D6 (0.62) | CYP2D6CYP2C19INPP5DCDC25APOLA1 | |
| SCHEMBL4729443 | 0.89 | CYP2D6 (0.65) | CYP2D6CYP2C19INPP5DCDC25APOLA1 | |
| SCHEMBL7514775 | 0.89 | CYP2D6 (0.62) | CYP2D6CYP2C19INPP5DCDC25APOLA1 | |
| Hydrochloric Acid SCHEMBL4728585 | 0.88 | INPP5D (0.66) | CYP2D6CYP2C19INPP5DCDC25APOLA1 | |
| SCHEMBL28959940 | 0.86 | CYP2D6 (0.58) | CYP2D6CYP2C19INPP5DCDC25APOLA1 | |
| SCHEMBL23496020 | 0.84 | CYP2D6 (0.56) | CYP2D6CYP2C19INPP5DCDC25APOLA1 | |
| SCHEMBL16227067 | 0.84 | CYP2D6 (0.63) | CYP2D6CYP2C19INPP5DCDC25APOLA1 | |
| SCHEMBL2155391 | 0.84 | CYP2D6 (0.63) | CYP2D6CYP2C19INPP5DCDC25APOLA1 | |
| SCHEMBL16225843 | 0.84 | CYP2D6 (0.63) | CYP2D6CYP2C19INPP5DCDC25APOLA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105452466-A | Aptamers and uses thereof | CARIS LIFE SCIENCES SWITZERLAND HOLDINGS S A R L | 2016-03-30 | — | — | CN | claimed |
| CN-105452466-A | Aptamers and uses thereof | CARIS LIFE SCIENCES SWITZERLAND HOLDINGS S A R L | 2016-03-30 | — | — | CN | disclosed |