SCHEMBL7514775

SCHEMBL7514775

CC(C)CCC[C@@H](C)[C@H]1CC[C@H]2[C@@H]3CCC4CCCC(O)(O)[C@]4(C)[C@H]3CC[C@]12C

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.62
CYP2C19 P33261 1/20 0.62
INPP5D Q92835 1/20 0.61
CDC25A P30304 5/20 0.56
CDC25B P30305 1/20 0.56
POLA1 P09884 1/20 0.56
NPC1L1 Q9UHC9 2/20 0.55
SRD5A1 P18405 4/20 0.53
SRD5A2 P31213 3/20 0.53
MEN1 O00255 2/20 0.53
LMNA P02545 2/20 0.53
KMT2A Q03164 2/20 0.53
AKR1B10 O60218 1/20 0.53
AKR1B1 P15121 1/20 0.53
EFNA1 P20827 1/20 0.53
EPHA2 P29317 1/20 0.53
PSEN1 P49768 1/20 0.53
PSEN2 P49810 1/20 0.53
GPBAR1 Q8TDU6 1/20 0.53
APH1B Q8WW43 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9664069 1.00 CYP2D6 (0.62) CYP2D6CYP2C19INPP5DCDC25ACDC25B
SCHEMBL15346210 0.91 CYP2D6 (0.62) CYP2D6CYP2C19INPP5DCDC25ACDC25B
SCHEMBL19064993 0.91 GPBAR1 (0.53) CYP2D6CYP2C19INPP5DCDC25AMEN1
SCHEMBL9580113 0.89 GPBAR1 (0.51) CYP2D6CYP2C19INPP5DCDC25APOLA1
SCHEMBL28057976 0.89 CYP2D6 (0.62) CYP2D6CYP2C19INPP5DCDC25ACDC25B
SCHEMBL1618569 0.89 GPBAR1 (0.54) CYP2D6CYP2C19INPP5DMEN1LMNA
SCHEMBL19064920 0.89 GPBAR1 (0.54) CYP2D6CYP2C19INPP5DMEN1LMNA
SCHEMBL28959940 0.88 CYP2D6 (0.58) CYP2D6CYP2C19INPP5DCDC25ACDC25B
SCHEMBL4729443 0.87 CYP2D6 (0.65) CYP2D6CYP2C19INPP5DCDC25ACDC25B
SCHEMBL1492159 0.87 CYP2D6 (0.62) CYP2D6CYP2C19INPP5DCDC25ACDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11185496-B2 Bioerodible implant for long-term drug delivery and associated methods of manufacture and use GESEA BIOSCIENCES, INC. (US) 2021-11-30 US claimed
CN-106535876-B Multivalent delivery of immunomodulators through liposomal spherical nucleic acids for prophylactic or therapeutic applications 埃克西奎雷股份有限公司 2020-09-11 CN claimed
US-20020183283-A1 Meiosis regulating compounds FAARUP PETER (DK) 2002-12-05 US claimed
US-20010003782-A1 Meiosis regulating compounds NOVA NORDISK A/S (DK) 2001-06-14 US claimed
US-11833244-B2 Bioerodible implant for long-term drug delivery and associated methods of manufacture and use Gesea Biosciences Inc. (US) 2023-12-05 US disclosed
CN-116497082-B Method for synthesizing 3 alpha, 7 alpha, 24R-trihydroxy cholesterol by chemical-enzymatic method 华南理工大学 2023-09-29 CN disclosed
EP-3368024-B1 COMPOSITIONS COMPRISING CANNABIDIOL AND SECOND THERAPEUTIC AGENTS FOR THE TREATMENT OF CANCER AKOS BIOSCIENCES INC (US) 2023-09-20 EP disclosed
CN-116497082-A Method for synthesizing 3 alpha, 7 alpha, 24R-trihydroxy cholesterol by chemical-enzymatic method 华南理工大学 2023-07-28 CN disclosed
US-20220249365-A1 BIOERODIBLE IMPLANT FOR LONG-TERM DRUG DELIVERY AND ASSOCIATED METHODS OF MANUFACTURE AND USE Gesea Biosciences Inc. (US) 2022-08-11 US disclosed
CN-114315947-A Novel method for synthesizing cholesterol and 25-hydroxycholesterol by using 22-sterol as raw material 上海敏韬医药科技有限公司 2022-04-12 CN disclosed
US-20220054429-A1 COMPOSITIONS COMPRISING CANNABIDIOL AND SECOND THERAPEUTIC AGENTS FOR THE TREATMENT OF CANCER AKOS BIOSCIENCES, INC. 2022-02-24 US disclosed
US-11185496-B2 Bioerodible implant for long-term drug delivery and associated methods of manufacture and use GESEA BIOSCIENCES, INC. (US) 2021-11-30 US disclosed
US-20180085305-A1 BIOERODIBLE IMPLANT FOR LONG-TERM DRUG DELIVERY AND ASSOCIATED METHODS OF MANUFACTURE AND USE Gesea Biosciences Inc. (US) 2018-03-29 US disclosed
WO-2017072773-A1 COMPOSITIONS COMPRISING CANNABIDIOL AND SECOND THERAPEUTIC AGENTS FOR THE TREATMENT OF CANCER NATHAN ILANA (IL) 2017-05-04 WO disclosed
CN-106537145-A Small molecule biochemical profiling of individual subjects for disease diagnosis and health assessment 麦特博隆股份有限公司 2017-03-22 CN disclosed
US-20010003782-A1 Meiosis regulating compounds NOVA NORDISK A/S (DK) 2001-06-14 US disclosed
EP-0203968-B1 METHOD FOR IMMUNOANALYSIS OF CHOLESTEROL EPOXIDES SCHAFFNER, Carl P. (US) 1992-04-08 EP disclosed
EP-0203968-A4 METHOD FOR IMMUNOANALYSIS OF CHOLESTEROL EPOXIDES. SCHAFFNER CARL P 1989-06-14 EP disclosed
EP-0203968-A1 METHOD FOR IMMUNOANALYSIS OF CHOLESTEROL EPOXIDES. SCHAFFNER CARL P 1986-12-10 EP disclosed
WO-1986003299-A1 METHOD FOR IMMUNOANALYSIS OF CHOLESTEROL EPOXIDES SCHAFFNER CARL P 1986-06-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020183283-A1 Meiosis regulating compounds SREBF2, SREBF1, TRIP13 CYP2D6 3846/4885CYP2C19 4130/4885INPP5D 1443/4885
US-20010003782-A1 Meiosis regulating compounds SREBF2, SREBF1, TRIP13 CYP2D6 3846/4885CYP2C19 4130/4885INPP5D 1443/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.