SCHEMBL28058258

SCHEMBL28058258

O=Cc1cc2ccc3ccc(O)c4ccc(c1)c2c34

nearest known ligand 0.51

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.44
PTGS2 P35354 1/20 0.44
RAB9A P51151 1/20 0.44
ERN1 O75460 8/20 0.41
ALDH5A1 P51649 3/20 0.37
ABAT P80404 3/20 0.37
ALDH1A1 P00352 2/20 0.37
TRIM24 O15164 1/20 0.37
HPGD P15428 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
TRIM33 Q9UPN9 1/20 0.37
ERBB2 P04626 1/20 0.36
CYP1A2 P05177 1/20 0.36
FYN P06241 1/20 0.36
MAOA P21397 1/20 0.36
ACHE P22303 1/20 0.36
AHR P35869 1/20 0.36
ESR1 P03372 1/20 0.36
ESR2 Q92731 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30989489 1.00 KDM4E (0.44) KDM4EPTGS2RAB9AERN1ALDH5A1
SCHEMBL9797581 0.79 CYP2A6 (0.41) KDM4EPTGS2RAB9AALDH5A1ABAT
SCHEMBL25272810 0.79 ERN1 (0.40) RAB9AERN1ALDH1A1TDP1ESR1
SCHEMBL22170089 0.78 CYP1A2 (0.42) ALDH1A1HPGDTDP1ERBB2CYP1A2
SCHEMBL5748274 0.78 ERBB2 (0.36) ALDH1A1HPGDTDP1ERBB2CYP1A2
SCHEMBL29968016 0.77 KDM4E (0.43) KDM4ERAB9AERN1TRIM24HPGD
SCHEMBL18605752 0.77 KDM4E (0.43) KDM4ERAB9AERN1TRIM24HPGD
SCHEMBL22170101 0.77 HSD17B10 (0.50) ALDH1A1HPGDTDP1ERBB2CYP1A2
SCHEMBL30849786 0.77 HSD17B10 (0.50) ALDH1A1HPGDTDP1ERBB2CYP1A2
SCHEMBL16144679 0.77 HSD17B10 (0.50) ALDH1A1HPGDTDP1ERBB2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105461615-A Preparation method of non-ionic fullerene-containing amphiphilic molecule UNIV SHANDONG 2016-04-06 CN claimed
CN-105461615-A Preparation method of non-ionic fullerene-containing amphiphilic molecule UNIV SHANDONG 2016-04-06 CN disclosed