Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | AGER | Q15109 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | ASPH | Q12797 | 1/20 | 0.48 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 3/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69939 | 0.97 | KDM4E (0.54) | KDM4EMAPTALDH1A1TSHRL3MBTL1 | |
| SCHEMBL29113117 | 0.94 | KDM4E (0.52) | KDM4EMAPTALDH1A1TSHRL3MBTL1 | |
| SCHEMBL27875395 | 0.94 | KDM4E (0.52) | KDM4EMAPTALDH1A1TSHRL3MBTL1 | |
| Water SCHEMBL335807 | 0.94 | KDM4E (0.52) | KDM4EMAPTALDH1A1TSHRL3MBTL1 | |
| Hydrochloric Acid SCHEMBL9356773 | 0.94 | KDM4E (0.52) | KDM4EMAPTALDH1A1TSHRL3MBTL1 | |
| SCHEMBL6345905 | 0.94 | KDM4E (0.52) | KDM4EMAPTALDH1A1TSHRL3MBTL1 | |
| Hydrochloric Acid SCHEMBL9356765 | 0.94 | KDM4E (0.52) | KDM4EMAPTALDH1A1TSHRL3MBTL1 | |
| Iodide SCHEMBL28827358 | 0.91 | KDM4E (0.52) | KDM4EMAPTALDH1A1TSHRL3MBTL1 | |
| Formic Acid SCHEMBL27879436 | 0.86 | KDM4E (0.46) | KDM4EMAPTALDH1A1TSHRL3MBTL1 | |
| SCHEMBL9630721 | 0.86 | KDM4E (0.48) | KDM4EMAPTALDH1A1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105440041-A | Synthetic method of 7-tert-butyl-2-ethyl-8-methyl-5,6-glyoxalidine[1,2-a] pyrazine-2,7(8H)-dicarboxylic acid | WUXI APPTEC CO LTD | 2016-03-30 | — | — | CN | claimed |
| CN-105440041-A | Synthetic method of 7-tert-butyl-2-ethyl-8-methyl-5,6-glyoxalidine[1,2-a] pyrazine-2,7(8H)-dicarboxylic acid | WUXI APPTEC CO LTD | 2016-03-30 | — | — | CN | disclosed |