Known targets — ChEMBL curated mechanism
GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRP known ✓ | O00591 | 1/20 | 0.38 |
| ▸ | GABRD known ✓ | O14764 | 1/20 | 0.38 |
| ▸ | GABRA1 known ✓ | P14867 | 1/20 | 0.38 |
| ▸ | GABRB1 known ✓ | P18505 | 1/20 | 0.38 |
| ▸ | GABRG2 known ✓ | P18507 | 1/20 | 0.38 |
| ▸ | GABRB3 known ✓ | P28472 | 1/20 | 0.38 |
| ▸ | GABRA5 known ✓ | P31644 | 1/20 | 0.38 |
| ▸ | GABRA3 known ✓ | P34903 | 1/20 | 0.38 |
| ▸ | GABRA2 known ✓ | P47869 | 1/20 | 0.38 |
| ▸ | GABRB2 known ✓ | P47870 | 1/20 | 0.38 |
| ▸ | GABRA4 known ✓ | P48169 | 1/20 | 0.38 |
| ▸ | GABRE known ✓ | P78334 | 1/20 | 0.38 |
| ▸ | GABRA6 known ✓ | Q16445 | 1/20 | 0.38 |
| ▸ | GABRG1 known ✓ | Q8N1C3 | 1/20 | 0.38 |
| ▸ | GABRG3 known ✓ | Q99928 | 1/20 | 0.38 |
| ▸ | GABRQ known ✓ | Q9UN88 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.52 |
| ▸ | ASPH | Q12797 | 3/20 | 0.52 |
| ▸ | KDM8 | Q8N371 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69939 | 0.94 | KDM4E (0.54) | KDM4EASPHKDM8MAPTALDH1A1 | |
| SCHEMBL28058447 | 0.91 | KDM4E (0.52) | KDM4EASPHKDM8MAPTALDH1A1 | |
| SCHEMBL27875395 | 0.91 | KDM4E (0.52) | KDM4EASPHKDM8MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL9356773 | 0.91 | KDM4E (0.52) | KDM4EASPHKDM8MAPTALDH1A1 | |
| SCHEMBL6345905 | 0.91 | KDM4E (0.52) | KDM4EASPHKDM8MAPTALDH1A1 | |
| SCHEMBL29113117 | 0.91 | KDM4E (0.52) | KDM4EASPHKDM8MAPTALDH1A1 | |
| Water SCHEMBL335807 | 0.91 | KDM4E (0.52) | KDM4EASPHKDM8MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL9356765 | 0.91 | KDM4E (0.52) | KDM4EASPHKDM8MAPTALDH1A1 | |
| Formic Acid SCHEMBL27879436 | 0.83 | KDM4E (0.46) | KDM4EASPHKDM8MAPTALDH1A1 | |
| SCHEMBL9630721 | 0.83 | KDM4E (0.48) | KDM4EASPHKDM8MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114829990-A | Method for manufacturing light valve and light valve manufactured by same | 吉特比 | 2022-07-29 | — | — | CN | disclosed |