Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | BLM | P54132 | 1/20 | 0.52 |
| ▸ | AGER | Q15109 | 1/20 | 0.52 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.52 |
| ▸ | ASPH | Q12797 | 1/20 | 0.48 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | NAPRT | Q6XQN6 | 3/20 | 0.44 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.44 |
| ▸ | MYC | P01106 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69939 | 0.97 | KDM4E (0.54) | KDM4EMAPTALDH1A1TSHRL3MBTL1 | |
| SCHEMBL27875395 | 0.94 | KDM4E (0.52) | KDM4EMAPTALDH1A1TSHRL3MBTL1 | |
| SCHEMBL28058447 | 0.94 | KDM4E (0.52) | KDM4EMAPTALDH1A1TSHRL3MBTL1 | |
| Water SCHEMBL335807 | 0.94 | KDM4E (0.52) | KDM4EMAPTALDH1A1TSHRL3MBTL1 | |
| Hydrochloric Acid SCHEMBL9356773 | 0.94 | KDM4E (0.52) | KDM4EMAPTALDH1A1TSHRL3MBTL1 | |
| Hydrochloric Acid SCHEMBL9356765 | 0.94 | KDM4E (0.52) | KDM4EMAPTALDH1A1TSHRL3MBTL1 | |
| SCHEMBL29113117 | 0.94 | KDM4E (0.52) | KDM4EMAPTALDH1A1TSHRL3MBTL1 | |
| Iodide SCHEMBL28827358 | 0.91 | KDM4E (0.52) | KDM4EMAPTALDH1A1TSHRL3MBTL1 | |
| Formic Acid SCHEMBL27879436 | 0.86 | KDM4E (0.46) | KDM4EMAPTALDH1A1TSHRL3MBTL1 | |
| SCHEMBL9630721 | 0.86 | KDM4E (0.48) | KDM4EMAPTALDH1A1TSHRL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6916816-B2 | Phenanthryl piperazinyl dicarboxylic acids as selective NMDA receptor modulating agents | THE BOARD OF REGENTS OF THE UNIVERSITY OF NEBRASKA (US) | 2005-07-12 | — | — | US | disclosed |
| EP-1244638-B1 | PHENANTHRYL PIPERAZINYL DICARBOXYLIC ACIDS AS SELECTIVE NMDA RECEPTOR MODULATING AGENTS | UNIV BRISTOL (GB) | 2004-05-12 | — | — | EP | disclosed |
| US-20030078237-A1 | Phenanthryl piperazinyl dicarboxylic acids as selective nmda receptor modulating agents | US ARMY, SECRETARY OF THE ARMY | 2003-04-24 | — | — | US | disclosed |
| EP-1244638-A2 | PHENANTHRYL PIPERAZINYL DICARBOXYLIC ACIDS AS SELECTIVE NMDA RECEPTOR MODULATING AGENTS | UNIVERSITY OF NEBRASKA BOARD OF REGENTS (US) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001044205-A2 | PHENANTHRYL PIPERAZINYL DICARBOXYLIC ACIDS AS SELECTIVE NMDA RECEPTOR MODULATING AGENTS | UNIVERSITY OF NEBRASKA BOARD OF REGENTS (US) | 2001-06-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030078237-A1 | Phenanthryl piperazinyl dicarboxylic acids as selective nmda receptor modulating agents | GRIK2, GRIK3, GRIK5 | KDM4E 2004/4885MAPT 4540/4885ALDH1A1 1895/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.