SCHEMBL2805861

SCHEMBL2805861

O=C1NC(=O)C(=Cc2ccc(O)c(O)c2)C(=O)N1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.68
MAPT P10636 3/20 0.68
KMT2A Q03164 2/20 0.68
MEN1 O00255 1/20 0.68
METAP1 P53582 3/20 0.66
PLK4 O00444 1/20 0.58
KDM4E B2RXH2 2/20 0.58
GAA P10253 1/20 0.58
LCK P06239 1/20 0.56
KDM1A O60341 1/20 0.55
ERO1A Q96HE7 1/20 0.55
CA2 P00918 2/20 0.54
CA12 O43570 1/20 0.54
CA1 P00915 1/20 0.54
CA7 P43166 1/20 0.54
CA9 Q16790 1/20 0.54
NOX4 Q9NPH5 1/20 0.53
MYC P01106 1/20 0.53
MAX P61244 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30020313 1.00 ALDH1A1 (0.68) ALDH1A1MAPTKMT2AMEN1METAP1
SCHEMBL30019611 0.86 METAP1 (0.58) ALDH1A1MAPTKMT2AMEN1METAP1
SCHEMBL14712974 0.86 METAP1 (0.58) ALDH1A1MAPTKMT2AMEN1METAP1
SCHEMBL10750025 0.84 GSK3B (0.67) ALDH1A1MAPTKMT2AMEN1KDM4E
SCHEMBL15421760 0.84 GSK3B (0.67) ALDH1A1MAPTKMT2AMEN1KDM4E
SCHEMBL10750021 0.84 GSK3B (0.67) ALDH1A1MAPTKMT2AMEN1KDM4E
SCHEMBL15421568 0.81 KMT2A (0.79) ALDH1A1MAPTKMT2AMEN1METAP1
SCHEMBL13848480 0.81 KMT2A (1.00) ALDH1A1MAPTKMT2AMEN1METAP1
SCHEMBL30019922 0.81 KMT2A (1.00) ALDH1A1MAPTKMT2AMEN1METAP1
SCHEMBL30020586 0.81 KMT2A (0.79) ALDH1A1MAPTKMT2AMEN1METAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022245120-A1 NOVEL COMPOUND AND COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR INHIBITING BIOFILM FORMATION OR VIRULENCE OF PATHOGENIC MICROORGANISM 부산대학교 산학협력단 2022-11-24 WO claimed
US-20160102065-A1 NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREOF PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) 2016-04-14 US claimed
WO-2022245120-A1 NOVEL COMPOUND AND COMPOSITION CONTAINING SAME AS ACTIVE INGREDIENT FOR INHIBITING BIOFILM FORMATION OR VIRULENCE OF PATHOGENIC MICROORGANISM 부산대학교 산학협력단 2022-11-24 WO disclosed
US-10682359-B2 Inhibitors of glucose kinases, along with methods of their formation and use UNIVERSITY OF SOUTH CAROLINA (US) 2020-06-16 US disclosed
US-9896421-B2 Compound having skin-whitening, anti-oxidizing and PPAR activities and medical use thereof PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) 2018-02-20 US disclosed
US-20160102065-A1 NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREOF PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) 2016-04-14 US disclosed
US-9216148-B2 Compound having skin-whitening, anti-oxidizing and PPAR activities and medical use therefor PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) 2015-12-22 US disclosed
US-20140023603-A1 NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREFOR PUSAN NATIONAL UNIVERSITY INDUSTRY-UNIVERSITY COOPERATION FOUNDATION (KR) 2014-01-23 US disclosed
US-8252490-B2 Color filter and solid state imaging device having a colored pattern formed from a curable composition FUJIFILM CORPORATION (JP) 2012-08-28 US disclosed
US-8252490-B2 Color filter and solid state imaging device having a colored pattern formed from a curable composition FUJIFILM CORPORATION (JP) 2012-08-28 US disclosed
EP-2036957-B1 Pigment dispersion liquid, curable composition, color filter, produced using the same, and solid state imaging device FUJIFILM CORP (JP) 2012-01-11 EP disclosed
US-7807074-B2 Gaseous dielectrics with low global warming potentials HONEYWELL INTERNATIONAL INC. (US) 2010-10-05 US disclosed
CN-101601103-A Gaseous Dielectrics with Low Global Warming Potential HONEYWELL INT INC (US) 2009-12-09 CN disclosed
EP-1305026-B1 BARBITURIC ACID ANALOGS AS THERAPEUTIC AGENTS NOVUSPHARMA SPA (IT) 2009-05-13 EP disclosed
EP-2036957-A2 Pigment dispersion liquid, curable composition, color filter, produced using the same, and solid state imaging device FUJIFILM Corporation (JP) 2009-03-18 EP disclosed
US-20090017273-A1 PIGMENT DISPERSION LIQUID, CURABLE COMPOSITION, COLOR FILTER PRODUCED USING THE SAME, AND SOLID STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2009-01-15 US disclosed
US-20090017273-A1 PIGMENT DISPERSION LIQUID, CURABLE COMPOSITION, COLOR FILTER PRODUCED USING THE SAME, AND SOLID STATE IMAGING DEVICE FUJIFILM CORPORATION (JP) 2009-01-15 US disclosed
US-20080135817-A1 Gaseous dielectrics with low global warming potentials HONEYWELL INTERNATIONAL INC. 2008-06-12 US disclosed
US-20080113993-A1 BARBITURIC ACID ANALOGS AS THERAPEUTIC AGENTS VIA ARIOSTO, 23 (IT) 2008-05-15 US disclosed
US-20080113993-A1 BARBITURIC ACID ANALOGS AS THERAPEUTIC AGENTS VIA ARIOSTO, 23 (IT) 2008-05-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140023603-A1 NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREFOR PPARG, PPARA, PPARD ALDH1A1 186/4885MAPT 2700/4885KMT2A 3139/4885
US-20160102065-A1 NOVEL COMPOUND HAVING SKIN-WHITENING, ANTI-OXIDIZING AND PPAR ACTIVITIES AND MEDICAL USE THEREOF PPARG, PPARA, TYR ALDH1A1 213/4885MAPT 1956/4885KMT2A 2641/4885
US-20080113993-A1 BARBITURIC ACID ANALOGS AS THERAPEUTIC AGENTS HIF1A, HIF1AN, PDGFA ALDH1A1 93/4885MAPT 3423/4885KMT2A 418/4885
US-10682359-B2 Inhibitors of glucose kinases, along with methods of their formation and use GCK, GCKR, GALK1 ALDH1A1 3609/4885MAPT 3958/4885KMT2A 1972/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.