Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 11/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | ATM | Q13315 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 3/20 | 0.54 |
| ▸ | GLA | P06280 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70233 | 0.89 | KDM4E (0.62) | NOTUMKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL1483525 | 0.86 | KDM4E (0.50) | NOTUMKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL9617019 | 0.86 | NOTUM (0.53) | NOTUMKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL17888585 | 0.86 | NOTUM (0.57) | NOTUMKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL29606243 | 0.86 | KDM4E (0.50) | NOTUMKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL31521444 | 0.86 | NOTUM (0.53) | NOTUMKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL2427491 | 0.84 | KDM4E (0.57) | NOTUMKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL10400378 | 0.83 | KDM4E (0.59) | KDM4EALDH1A1HSD17B10HPGDATM | |
| SCHEMBL27442421 | 0.83 | NOTUM (0.58) | NOTUMKDM4EALDH1A1HSD17B10HPGD | |
| SCHEMBL11328242 | 0.81 | KDM4E (0.58) | NOTUMKDM4EALDH1A1HSD17B10HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104066330-B | Isoxazoline derivatives for controlling ectoparasites | ANACOR PHARMACEUTICALS, INC. (US) | 2016-05-18 | — | — | CN | disclosed |