Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.50 |
| ▸ | CA1 | P00915 | 3/20 | 0.50 |
| ▸ | CA2 | P00918 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 2/20 | 0.50 |
| ▸ | GLA | P06280 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CASP1 | P29466 | 1/20 | 0.50 |
| ▸ | CASP7 | P55210 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | LCK | P06239 | 1/20 | 0.49 |
| ▸ | FYN | P06241 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31521444 | 1.00 | NOTUM (0.53) | NOTUMKDM4EALDH1A1HSD17B10CA1 | |
| SCHEMBL851742 | 0.89 | KDM4E (0.58) | NOTUMKDM4EALDH1A1HSD17B10CA1 | |
| SCHEMBL15878431 | 0.86 | NOTUM (0.53) | NOTUMKDM4EALDH1A1HSD17B10CA1 | |
| SCHEMBL28058610 | 0.86 | NOTUM (0.57) | NOTUMKDM4EALDH1A1HSD17B10CA1 | |
| SCHEMBL4914225 | 0.86 | KDM4E (0.46) | NOTUMKDM4EALDH1A1HSD17B10CA1 | |
| SCHEMBL10400378 | 0.83 | KDM4E (0.59) | KDM4EALDH1A1HSD17B10CA1CA2 | |
| SCHEMBL310059 | 0.82 | MAPT (0.60) | KDM4EALDH1A1HSD17B10CA1CA2 | |
| SCHEMBL3767347 | 0.81 | KDM4E (0.62) | KDM4EALDH1A1HSD17B10CA1CA2 | |
| SCHEMBL9080431 | 0.81 | KDM4E (0.62) | KDM4EALDH1A1HSD17B10CA1CA2 | |
| SCHEMBL30967314 | 0.81 | KDM4E (0.62) | KDM4EALDH1A1HSD17B10CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4210687-A | — | — | None | — | — | JP | disclosed |
| EP-4577537-A1 | SUBSTITUTED BICYCLES AS HSET INHIBITORS | Merck Patent GmbH (DE) | 2025-07-02 | — | — | EP | disclosed |
| WO-2024042007-A1 | SUBSTITUTED BICYCLES AS HSET INHIBITORS | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | WO | disclosed |
| CN-109563094-A | Acyclic derivatives, their preparation method and the pharmaceutical composition containing them that new (miscellaneous) aryl replaces | 法国施维雅药厂 | 2019-04-02 | — | — | CN | disclosed |
| WO-2016001452-A1 | COMPOUNDS, IN PARTICULAR FOR USE IN THE TREATMENT OF A DISEASE OR CONDITION FOR WHICH A BROMODOMAIN INHIBITOR IS INDICATED | Universität Zürich (CH) | 2016-01-07 | — | — | WO | disclosed |
| JP-H04210687-A | HYDROISOCOUMARIN DERIVATIVE | MITSUBISHI RAYON CO LTD | 1992-07-31 | — | — | JP | disclosed |