Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LATS1 | O95835 | 3/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.37 |
| ▸ | MAP4K4 | O95819 | 3/20 | 0.36 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | FRK | P42685 | 2/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.36 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.36 |
| ▸ | FLT3 | P36888 | 2/20 | 0.35 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.35 |
| ▸ | MAP4K5 | Q9Y4K4 | 2/20 | 0.35 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.35 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.35 |
| ▸ | PRKACA | P17612 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.35 |
| ▸ | SLK | Q9H2G2 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.35 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28058704 | 0.72 | PIK3CA (0.41) | LATS1ADORA1GSK3BADORA2ALATS2 | |
| SCHEMBL28058618 | 0.71 | LATS1 (0.39) | LATS1ADORA2BMAPK9ADORA1MAPK10 | |
| SCHEMBL29430257 | 0.65 | TP53 (0.48) | LATS1MAP4K4EGFRFRKMAPK9 | |
| SCHEMBL25295479 | 0.65 | TP53 (0.48) | LATS1MAP4K4EGFRFRKMAPK9 | |
| SCHEMBL5989213 | 0.65 | HSP90AA1 (0.44) | LATS1MAP4K4EGFRFRKMAPK9 | |
| SCHEMBL2814353 | 0.64 | HSP90AA1 (0.52) | LATS1MAP4K4EGFRFRKMAPK9 | |
| SCHEMBL30595872 | 0.64 | HSP90AA1 (0.52) | LATS1MAP4K4EGFRFRKMAPK9 | |
| SCHEMBL28038682 | 0.64 | HSP90AA1 (0.50) | LATS1ADORA2BMAPK9ADORA1GSK3B | |
| SCHEMBL19409904 | 0.64 | HSP90AA1 (0.45) | LATS1ADORA2BMAPK9ADORA1MAPK10 | |
| SCHEMBL5270117 | 0.64 | NNMT (0.43) | MAP4K4ADORA3P2RX7HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105473570-A | Diaminoheteroaryl substituted pyrazoles | Bayer Pharma AG | 2016-04-06 | — | — | CN | claimed |
| CN-105473570-A | Diaminoheteroaryl substituted pyrazoles | Bayer Pharma AG | 2016-04-06 | — | — | CN | disclosed |