Biphenyl

Biphenyl

SCHEMBL28058633

CC1(C)c2ccccc2Oc2cccc(P)c21.c1ccc(-c2ccccc2)cc1

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.33
DRD1 P21728 1/20 0.33
LPL P06858 1/20 0.31
LIPG Q9Y5X9 1/20 0.31
CHRM3 P20309 1/20 0.30
AHR P35869 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27630608 0.93 AHR (0.33) DRD1CHRM3AHR
SCHEMBL31125706 0.92 DRD1 (0.33) DRD1CHRM3AHR
SCHEMBL13324537 0.75 ALOX5 (0.35) CHRM3AHR
SCHEMBL22773736 0.75 DRD1 (0.39) DRD1CHRM3AHR
SCHEMBL15074809 0.75 DRD1 (0.42) DRD1AHR
SCHEMBL47009 0.74 ALOX5 (0.44) DRD1CHRM3AHR
SCHEMBL29360424 0.74 ALOX5 (0.44) DRD1CHRM3AHR
SCHEMBL25704818 0.74 ALOX5 (0.34) DRD1CHRM3AHR
SCHEMBL3822701 0.74 ALDH1A1 (0.34) DRD1
SCHEMBL23696795 0.73 AHR (0.50) BACE1DRD1CHRM3AHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105473584-A Thiophene- or furan-substituted isothiazoline compounds as pesticides MERIAL LTD 2016-04-06 CN disclosed
CN-101622240-A Fused Substituted Aminopyrrolidine Derivatives DAIICHI SANKYO CO LTD 2010-01-06 CN disclosed