Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SNCA | P37840 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 2/20 | 0.40 |
| ▸ | THRA | P10827 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL586998 | 0.86 | HTT (0.53) | TSHRALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL11359239 | 0.83 | PTGDR2 (0.52) | TSHRALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL27859116 | 0.79 | THRA (0.42) | TSHRALDH1A1KMT2AMEN1LMNA | |
| SCHEMBL15650282 | 0.79 | PTGDR2 (0.51) | ALDH1A1KMT2AMEN1MAPK1LMNA | |
| SCHEMBL8908642 | 0.77 | PPARG (0.47) | TSHRLMNATHRBTHRAHTR2A | |
| SCHEMBL7902120 | 0.75 | KMT2A (0.48) | ALDH1A1KMT2AMEN1MAPK1LMNA | |
| SCHEMBL656861 | 0.75 | SNCA (0.54) | TSHRALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL15933189 | 0.75 | KDM4E (0.51) | ALDH1A1KMT2AMEN1MAPK1SNCA | |
| SCHEMBL28744678 | 0.75 | GAA (0.43) | TSHRALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL31457256 | 0.75 | HTR2A (0.46) | TSHRALDH1A1HTR2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105439914-A | 4-aminoacylphenoxyacetamide compound and medicine uses thereof | UNIV FUDAN | 2016-03-30 | — | — | CN | disclosed |
| CN-105439914-A | 4-aminoacylphenoxyacetamide compound and medicine uses thereof | UNIV FUDAN | 2016-03-30 | — | — | CN | disclosed |