Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.47 |
| ▸ | ALOX5 | P09917 | 3/20 | 0.45 |
| ▸ | AKT1 | P31749 | 1/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 6/20 | 0.42 |
| ▸ | LTA4H | P09960 | 1/20 | 0.42 |
| ▸ | FPR1 | P21462 | 2/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27859116 | 0.88 | THRA (0.42) | PPARGPPARAALOX5LTA4HTHRA | |
| SCHEMBL1875344 | 0.85 | AKT1 (0.49) | ALOX5AKT1CYP19A1AKR1C3AKR1C2 | |
| SCHEMBL27306758 | 0.83 | TYR (0.51) | PPARGPPARAALOX5AKT1TRPV1 | |
| SCHEMBL28744678 | 0.80 | GAA (0.43) | CYP19A1HTR2ATSHR | |
| SCHEMBL29113872 | 0.80 | ALOX5 (0.55) | PPARGPPARAALOX5CYP19A1TRPV1 | |
| SCHEMBL28324628 | 0.79 | GAA (0.50) | CYP19A1HTR2ATSHR | |
| SCHEMBL23306718 | 0.79 | ALOX5 (0.60) | PPARGPPARAALOX5TRPV1PTGS2 | |
| SCHEMBL23714926 | 0.79 | ALOX5 (0.60) | PPARGPPARAALOX5TRPV1PTGS2 | |
| SCHEMBL1788428 | 0.78 | PPARG (0.62) | PPARGPPARAPTGS2FPR1THRA | |
| SCHEMBL12799802 | 0.77 | ALOX5 (0.56) | PPARGPPARAALOX5LTA4HFPR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5684202-A | AMINE ACCELERATORS AND TERMINATED EPOXY RESINS OR POLYEPOXIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-11-04 | — | — | US | disclosed |