Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | PLAU | P00749 | 1/20 | 0.44 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.44 |
| ▸ | ELANE | P08246 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28058908 | 0.88 | CA1 (0.46) | ALDH1A1KDM4ELMNARECQLMAPT | |
| SCHEMBL2330773 | 0.86 | KDM4E (0.70) | ALDH1A1KDM4ELMNAF2PLAU | |
| SCHEMBL28058971 | 0.83 | RECQL (0.47) | ALDH1A1KDM4ELMNARECQLMAPT | |
| SCHEMBL12803579 | 0.79 | VEGFA (0.51) | ALDH1A1KDM4ERECQLMAPTKMT2A | |
| SCHEMBL9589872 | 0.75 | ALDH1A1 (0.58) | ALDH1A1KDM4ELMNARECQLMAPT | |
| SCHEMBL12391316 | 0.75 | ALDH1A1 (0.42) | ALDH1A1KDM4ELMNARECQLMAPT | |
| SCHEMBL31373551 | 0.74 | ALDH1A1 (0.41) | ALDH1A1KDM4ELMNARECQLMAPT | |
| SCHEMBL2334312 | 0.74 | ALDH1A1 (0.54) | ALDH1A1KDM4ELMNARECQLMAPT | |
| SCHEMBL2330297 | 0.74 | KDM4E (0.57) | ALDH1A1KDM4ELMNAELANETDP1 | |
| SCHEMBL29190981 | 0.73 | F2 (0.56) | ALDH1A1KDM4ELMNAF2PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102844318-B | Be used for the treatment of the compound of respiratory syncytial virus infection | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2016-04-13 | — | — | CN | disclosed |