Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 4/20 | 0.46 |
| ▸ | CA2 | P00918 | 4/20 | 0.46 |
| ▸ | CA12 | O43570 | 2/20 | 0.46 |
| ▸ | CA7 | P43166 | 2/20 | 0.46 |
| ▸ | CA9 | Q16790 | 2/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | P4HB | P07237 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28058807 | 0.88 | ALDH1A1 (0.54) | ALDH1A1LMNAGAAMAPTKDM4E | |
| SCHEMBL2334312 | 0.86 | ALDH1A1 (0.54) | CA1CA2CA12CA7CA9 | |
| SCHEMBL9589872 | 0.76 | ALDH1A1 (0.58) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL12391316 | 0.76 | ALDH1A1 (0.42) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL31373551 | 0.75 | ALDH1A1 (0.41) | CA1CA2CA12CA9ALDH1A1 | |
| SCHEMBL2330853 | 0.74 | ALDH1A1 (0.53) | ALDH1A1LMNAGAAMAPTKDM4E | |
| SCHEMBL2330773 | 0.74 | KDM4E (0.70) | ALDH1A1LMNAGAAMAPTKDM4E | |
| SCHEMBL2333971 | 0.74 | ALDH1A1 (0.53) | CA1CA2ALDH1A1LMNAGAA | |
| SCHEMBL2334137 | 0.73 | ALDH1A1 (0.52) | ALDH1A1LMNAMAPTKDM4EMEN1 | |
| SCHEMBL11357348 | 0.73 | NR4A2 (0.47) | CA1CA2CA12CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102844318-B | Be used for the treatment of the compound of respiratory syncytial virus infection | BIOTA SCIENTIFIC MANAGEMENT PTY LTD. (AU) | 2016-04-13 | — | — | CN | disclosed |