Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | F9 | P00740 | 1/20 | 0.31 |
| ▸ | F10 | P00742 | 1/20 | 0.31 |
| ▸ | F12 | P00748 | 1/20 | 0.31 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | F7 | P08709 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.31 |
| ▸ | DPP4 | P27487 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL28724275 | 1.00 | PKM (0.35) | PKMHRH4F2F9F10 | |
| SCHEMBL1505813 | 0.84 | LMNA (0.31) | — | |
| SCHEMBL2456274 | 0.84 | LMNA (0.31) | — | |
| SCHEMBL2309048 | 0.84 | LMNA (0.31) | — | |
| Hydrochloric Acid SCHEMBL31094833 | 0.82 | LMNA (0.33) | — | |
| Trifluoroacetic Acid SCHEMBL26113693 | 0.82 | DPP4 (0.38) | PKMHRH4F2F9F10 | |
| Trifluoroacetic Acid SCHEMBL21816711 | 0.80 | PKM (0.36) | PKMHRH4F2F9F10 | |
| Trifluoroacetic Acid SCHEMBL21816594 | 0.80 | PKM (0.36) | PKMHRH4F2F9F10 | |
| Trifluoroacetic Acid SCHEMBL2917931 | 0.80 | PKM (0.36) | PKMHRH4F2F9F10 | |
| Trifluoroacetic Acid SCHEMBL26600122 | 0.77 | DPP4 (0.38) | PKMHRH4F2F9F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105461697-A | Quinazolinone PARP-1 inhibitors, medicinal composition containing inhibitors, and antitumor use of inhibitors | INST MATERIA MEDICA CAMS | 2016-04-06 | — | — | CN | disclosed |