Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.41 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.41 |
| ▸ | MAPK10 | P53779 | 5/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28059001 | 0.81 | MAPK10 (0.61) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL28059002 | 0.74 | PIK3C3 (0.52) | MEN1KMT2ANPC1RAB9AALDH1A1 | |
| SCHEMBL5789745 | 0.74 | CDK4 (0.62) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL8230360 | 0.73 | MAPT (0.42) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL28059017 | 0.72 | CDK4 (0.64) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL28059097 | 0.70 | CDK4 (0.46) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL8084192 | 0.69 | MAPT (0.51) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL330449 | 0.68 | MAPT (0.53) | MEN1KMT2AMAPTNPC1RAB9A | |
| SCHEMBL28059096 | 0.68 | MAPK10 (0.68) | MAPK10DYRK1ACDK2CDK4CCNE1 | |
| SCHEMBL1883531 | 0.68 | MAPK14 (0.45) | MEN1KMT2AMAPTNPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105585565-A | 2-phenylamino-4-thiazolyl pyridine derivatives, preparing method thereof, pharmaceutical compositions of the derivatives and uses of the derivatives | INST MATERIA MEDICA CAMS | 2016-05-18 | — | — | CN | disclosed |