Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 10/20 | 0.52 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HTR1F | P30939 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28059033 | 0.80 | SORT1 (0.44) | PIK3C3MEN1KMT2ANPC1RAB9A | |
| SCHEMBL28059092 | 0.77 | MAPK14 (0.52) | MEN1KMT2AMAPK14L3MBTL1TDP1 | |
| SCHEMBL28059011 | 0.75 | ABCB1 (0.47) | MEN1KMT2AMAPK14L3MBTL1USP2 | |
| SCHEMBL28059025 | 0.74 | MEN1 (0.41) | PIK3C3MEN1KMT2ANPC1RAB9A | |
| SCHEMBL3075444 | 0.73 | GPR52 (0.47) | MEN1KMT2ANPC1RAB9ALMNA | |
| SCHEMBL28059020 | 0.73 | AURKA (0.55) | MEN1KMT2ANPC1RAB9AMAPK14 | |
| SCHEMBL17001118 | 0.72 | PIK3C3 (0.74) | PIK3C3 | |
| SCHEMBL28059001 | 0.72 | MAPK10 (0.61) | MEN1KMT2ANPC1RAB9AUSP2 | |
| SCHEMBL28059009 | 0.71 | MEN1 (0.46) | MEN1KMT2ANPC1RAB9AL3MBTL1 | |
| SCHEMBL28059097 | 0.70 | CDK4 (0.46) | MEN1KMT2ANPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105585565-A | 2-phenylamino-4-thiazolyl pyridine derivatives, preparing method thereof, pharmaceutical compositions of the derivatives and uses of the derivatives | INST MATERIA MEDICA CAMS | 2016-05-18 | — | — | CN | claimed |
| CN-105585565-A | 2-phenylamino-4-thiazolyl pyridine derivatives, preparing method thereof, pharmaceutical compositions of the derivatives and uses of the derivatives | INST MATERIA MEDICA CAMS | 2016-05-18 | — | — | CN | disclosed |