Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.68 |
| ▸ | TSHR | P16473 | 3/20 | 0.68 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | AVPR2 | P30518 | 8/20 | 0.64 |
| ▸ | AVPR1A | P37288 | 7/20 | 0.64 |
| ▸ | OXTR | P30559 | 3/20 | 0.64 |
| ▸ | CA1 | P00915 | 1/20 | 0.63 |
| ▸ | CA2 | P00918 | 1/20 | 0.63 |
| ▸ | CA7 | P43166 | 1/20 | 0.63 |
| ▸ | CA9 | Q16790 | 1/20 | 0.63 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.63 |
| ▸ | POLB | P06746 | 1/20 | 0.61 |
| ▸ | MAPT | P10636 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3456488 | 0.85 | HPGD (0.83) | ALDH1A1TSHRHPGDLMNAAVPR2 | |
| SCHEMBL7348349 | 0.84 | AVPR2 (0.76) | ALDH1A1TSHRHPGDLMNAAVPR2 | |
| SCHEMBL6198498 | 0.84 | ALDH1A1 (0.81) | ALDH1A1TSHRHPGDAVPR2AVPR1A | |
| SCHEMBL29463754 | 0.84 | ALDH1A1 (0.81) | ALDH1A1TSHRHPGDAVPR2AVPR1A | |
| SCHEMBL4493929 | 0.83 | ALDH1A1 (0.71) | ALDH1A1TSHRHPGDLMNAAVPR2 | |
| SCHEMBL6965406 | 0.82 | AVPR2 (0.92) | ALDH1A1TSHRHPGDLMNAAVPR2 | |
| SCHEMBL7349843 | 0.82 | AVPR2 (0.72) | ALDH1A1TSHRHPGDLMNAAVPR2 | |
| SCHEMBL383818 | 0.81 | HSP90AA1 (0.61) | ALDH1A1TSHRHPGDLMNACA1 | |
| SCHEMBL7345049 | 0.81 | TSHR (0.76) | ALDH1A1TSHRHPGDLMNAAVPR2 | |
| SCHEMBL2164159 | 0.80 | ALDH1A1 (0.66) | ALDH1A1TSHRHPGDLMNAAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105585526-A | Preparation method of 1-(4-tert-butyl-benzoyl)tetrahydroquinoline | TIANJIN HEOWNS BIOCHEMISTRY TECH CO LTD | 2016-05-18 | — | — | CN | disclosed |
| CN-105585526-A | Preparation method of 1-(4-tert-butyl-benzoyl)tetrahydroquinoline | TIANJIN HEOWNS BIOCHEMISTRY TECH CO LTD | 2016-05-18 | — | — | CN | disclosed |