Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 1/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.47 |
| ▸ | GHSR | Q92847 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28059322 | 0.91 | USP30 (0.52) | SLC6A2SLC6A4SLC6A3MAPTALDH1A1 | |
| SCHEMBL1031264 | 0.91 | USP30 (0.52) | SLC6A2SLC6A4SLC6A3MAPTALDH1A1 | |
| SCHEMBL8247003 | 0.91 | USP30 (0.52) | SLC6A2SLC6A4SLC6A3MAPTALDH1A1 | |
| SCHEMBL29796085 | 0.89 | GPR119 (0.53) | SLC6A2SLC6A4SLC6A3MAPTALDH1A1 | |
| SCHEMBL2481879 | 0.89 | GPR119 (0.53) | SLC6A2SLC6A4SLC6A3MAPTALDH1A1 | |
| SCHEMBL22735288 | 0.87 | MAPT (0.45) | SLC6A2SLC6A4SLC6A3MAPTALDH1A1 | |
| SCHEMBL22735308 | 0.87 | MAPT (0.45) | SLC6A2SLC6A4SLC6A3MAPTALDH1A1 | |
| SCHEMBL22735290 | 0.87 | MAPT (0.45) | SLC6A2SLC6A4SLC6A3MAPTALDH1A1 | |
| SCHEMBL22772006 | 0.87 | MAPT (0.45) | SLC6A2SLC6A4SLC6A3MAPTALDH1A1 | |
| SCHEMBL22735303 | 0.87 | MAPT (0.45) | SLC6A2SLC6A4SLC6A3MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105384695-A | Pyrimidine derivative, preparation method therefor and application thereof in medicine | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2016-03-09 | — | — | CN | disclosed |