Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.52 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.47 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.43 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.42 |
| ▸ | GHSR | Q92847 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1031264 | 1.00 | USP30 (0.52) | USP30SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL8247003 | 1.00 | USP30 (0.52) | USP30SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL2481879 | 0.94 | GPR119 (0.53) | USP30SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL29796085 | 0.94 | GPR119 (0.53) | USP30SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL28059263 | 0.91 | SLC6A2 (0.49) | USP30SLC6A2SLC6A4SLC6A3ALDH1A1 | |
| SCHEMBL596200 | 0.87 | ALDH1A1 (0.57) | USP30ALDH1A1MAPTLMNAGPR119 | |
| SCHEMBL596199 | 0.87 | ALDH1A1 (0.57) | USP30ALDH1A1MAPTLMNAGPR119 | |
| SCHEMBL15377781 | 0.87 | ALDH1A1 (0.57) | USP30ALDH1A1MAPTLMNAGPR119 | |
| SCHEMBL4707629 | 0.84 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT | |
| SCHEMBL22735334 | 0.84 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105384695-A | Pyrimidine derivative, preparation method therefor and application thereof in medicine | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2016-03-09 | — | — | CN | disclosed |