Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | GLA | P06280 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.39 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.39 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4662906 | 0.83 | NNMT (0.51) | NNMTKDM4EGAAALDH1A1GLA | |
| SCHEMBL2674736 | 0.80 | KDM4E (0.49) | NNMTKDM4EGAAALDH1A1GLA | |
| SCHEMBL15525456 | 0.76 | IRAK4 (0.51) | NNMTKDM4ESMN1; SMN2MKNK1MKNK2 | |
| SCHEMBL28628579 | 0.75 | SMN1; SMN2 (0.62) | NNMTKDM4EPOLBSMN1; SMN2L3MBTL1 | |
| SCHEMBL15648561 | 0.74 | KDM4E (0.44) | NNMTKDM4EGAAALDH1A1GLA | |
| SCHEMBL17371698 | 0.73 | TDP1 (0.53) | KDM4EALDH1A1HPGDPOLBL3MBTL1 | |
| SCHEMBL21198869 | 0.72 | POLB (0.45) | KDM4EGAAALDH1A1GLAHPGD | |
| SCHEMBL3345488 | 0.72 | NNMT (0.53) | NNMTKDM4EGAAALDH1A1GLA | |
| SCHEMBL28285146 | 0.71 | CYP3A4 (0.61) | KDM4EGAAALDH1A1GLAHPGD | |
| SCHEMBL10222121 | 0.71 | NNMT (0.51) | NNMTKDM4EGAAALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103319408-B | For the compound of prevention and therapy cardiovascular disorder | RESVERLOGIX CORP. (CA) (CA) | 2016-04-13 | — | — | CN | disclosed |