Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.57 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | PPARA | Q07869 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28059388 | 0.95 | TSHR (0.51) | TSHRFFAR4ACHESMN1; SMN2POLB | |
| SCHEMBL28059505 | 0.93 | POLB (0.52) | TSHRFFAR4ACHESMN1; SMN2POLB | |
| SCHEMBL28059563 | 0.93 | POLB (0.52) | TSHRFFAR4ACHESMN1; SMN2POLB | |
| SCHEMBL28059500 | 0.93 | POLB (0.52) | TSHRFFAR4ACHESMN1; SMN2POLB | |
| SCHEMBL7563849 | 0.85 | POLB (0.51) | TSHRFFAR4SMN1; SMN2POLBMAPK1 | |
| SCHEMBL13901335 | 0.82 | TUBB1 (0.60) | FFAR4FFAR1PPARAALDH1A1 | |
| SCHEMBL5843043 | 0.81 | POLB (0.54) | TSHRFFAR4SMN1; SMN2POLBMAPK1 | |
| SCHEMBL27997143 | 0.80 | PPARA (0.62) | TSHRACHESMN1; SMN2SYKPPARA | |
| SCHEMBL10835043 | 0.79 | ACHE (0.48) | TSHRACHESMN1; SMN2POLBMAPK1 | |
| SCHEMBL12431884 | 0.78 | ACHE (0.56) | ACHESMN1; SMN2MAPK1LMNASYK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105418412-A | Hypoglycemic active compound and pharmaceutical application thereof | INST PHARMACOLOGY & TOXICOLOGY ACAD MILITARY MEDICAL SCIENCES PLA CHINA | 2016-03-23 | — | — | CN | claimed |
| CN-105418412-A | Hypoglycemic active compound and pharmaceutical application thereof | INST PHARMACOLOGY & TOXICOLOGY ACAD MILITARY MEDICAL SCIENCES PLA CHINA | 2016-03-23 | — | — | CN | disclosed |