Known targets — ChEMBL curated mechanism
KCNA1KCNA10KCNA2KCNA3KCNA4KCNA5KCNA6KCNA7KCNB1KCNB2KCNC1KCNC2KCNC3KCNC4KCND1KCND2KCND3KCNF1KCNG1KCNG2KCNG3KCNG4KCNH1KCNH2KCNH3KCNH4KCNH5KCNH6KCNH7KCNH8KCNQ1KCNQ2KCNQ3KCNQ4KCNQ5KCNS1KCNS2KCNS3KCNV1KCNV2
The experimentally established mechanism targets of Guanidine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL779306 | 0.88 | — | — | |
| SCHEMBL33154 | 0.88 | — | — | |
| Ammonia Solution, Strong SCHEMBL3253405 | 0.85 | — | — | |
| SCHEMBL28026670 | 0.76 | — | — | |
| SCHEMBL3113903 | 0.71 | CA5A (0.36) | CYP2C19BLM | |
| SCHEMBL8895269 | 0.71 | CA5A (0.36) | CYP2C19BLM | |
| SCHEMBL1162668 | 0.67 | — | — | |
| SCHEMBL544529 | 0.67 | — | — | |
| SCHEMBL18691188 | 0.67 | LMNA (0.31) | CYP2C19BLM | |
| SCHEMBL4353203 | 0.67 | LMNA (0.31) | CYP2C19BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105593208-A | Process for synthesizing fluoroalkyl sulfonate | SOLVAY SPECIALTY POLYMERS IT | 2016-05-18 | — | — | CN | disclosed |