Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | PYCR1 | P32322 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | BLM | P54132 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | AGER | Q15109 | 3/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL515999 | 0.84 | G6PC1 (0.54) | USP2TSHRALDH1A1G6PC1SLC6A2 | |
| SCHEMBL7885548 | 0.84 | G6PC1 (0.54) | USP2TSHRALDH1A1G6PC1SLC6A2 | |
| SCHEMBL28410816 | 0.84 | G6PC1 (0.54) | USP2TSHRALDH1A1G6PC1SLC6A2 | |
| SCHEMBL28784253 | 0.84 | G6PC1 (0.45) | USP2TSHRALDH1A1G6PC1SLC6A2 | |
| SCHEMBL3373138 | 0.82 | SLC6A2 (0.51) | USP2TSHRALDH1A1G6PC1SLC6A2 | |
| SCHEMBL13017781 | 0.80 | SLC6A2 (0.53) | TSHRALDH1A1G6PC1SLC6A2SLC6A4 | |
| SCHEMBL9455273 | 0.78 | GRIN2B (0.58) | USP2ALDH1A1G6PC1SLC6A2SLC6A4 | |
| SCHEMBL10708848 | 0.78 | G6PC1 (0.49) | USP2TSHRALDH1A1G6PC1SLC6A2 | |
| SCHEMBL11880676 | 0.77 | KMT2A (0.49) | USP2TSHRALDH1A1SMN1; SMN2G6PC1 | |
| Hydrochloric Acid SCHEMBL9454768 | 0.77 | GRIN2B (0.57) | USP2ALDH1A1G6PC1SLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105481699-B | A kind of method for synthesizing the propargylamine derivative for containing different substituents at alkynes end | 复旦大学 | 2017-12-01 | — | — | CN | disclosed |
| CN-105481699-A | Method for synthesizing propargylamine derivative with different substituent groups at alkyne terminal | UNIV FUDAN | 2016-04-13 | — | — | CN | disclosed |