Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PC1 | P35575 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | AGER | Q15109 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | YTHDC1 | Q96MU7 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28410816 | 0.84 | G6PC1 (0.54) | G6PC1SLC6A2SLC6A4AGERALDH1A1 | |
| SCHEMBL515999 | 0.84 | G6PC1 (0.54) | G6PC1SLC6A2SLC6A4AGERALDH1A1 | |
| SCHEMBL7885548 | 0.84 | G6PC1 (0.54) | G6PC1SLC6A2SLC6A4AGERALDH1A1 | |
| SCHEMBL28059587 | 0.84 | LMNA (0.49) | G6PC1SLC6A2SLC6A4AGERALDH1A1 | |
| SCHEMBL3373138 | 0.82 | SLC6A2 (0.51) | G6PC1SLC6A2SLC6A4AGERALDH1A1 | |
| SCHEMBL13017781 | 0.80 | SLC6A2 (0.53) | G6PC1SLC6A2SLC6A4AGERALDH1A1 | |
| SCHEMBL11966311 | 0.79 | SLC18A3 (0.58) | G6PC1ALDH1A1MEN1KMT2ALTA4H | |
| SCHEMBL11895258 | 0.79 | SLC18A3 (0.58) | G6PC1ALDH1A1MEN1KMT2ALTA4H | |
| SCHEMBL9455273 | 0.78 | GRIN2B (0.58) | G6PC1SLC6A2SLC6A4AGERALDH1A1 | |
| SCHEMBL10708848 | 0.78 | G6PC1 (0.49) | G6PC1SLC6A2SLC6A4AGERALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101759598-B | Tetracycline compounds with aminoalkylamidines | SHANDONG XUANZHU MEDICAL TECHNOLOGY CO LTD | 2011-11-09 | — | — | CN | disclosed |
| CN-101759598-A | Tetracycline compounds with aminoalkylamidines | SHANDONG XUANZHU PHARM TECH CO | 2010-06-30 | — | — | CN | disclosed |