Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 11/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL751258 | 0.79 | PRCP (0.42) | PRCPCYP3A4CYP2C9CYP1A2NR1I2 | |
| SCHEMBL9980237 | 0.73 | PRCP (0.45) | PRCPCYP3A4CYP2C9CYP1A2NR1I2 | |
| SCHEMBL883052 | 0.73 | PRCP (0.48) | PRCPCYP3A4CYP2C9CYP1A2NR1I2 | |
| SCHEMBL19578300 | 0.72 | PRCP (0.46) | PRCPCYP3A4CYP2C9CYP1A2NR1I2 | |
| SCHEMBL12175097 | 0.70 | KCNH2 (0.50) | PRCPCYP3A4CYP2C9CYP1A2NR1I2 | |
| SCHEMBL12175082 | 0.70 | KCNH2 (0.62) | PRCPCYP3A4CYP2C9CYP1A2NR1I2 | |
| SCHEMBL12175205 | 0.70 | CYP3A4 (0.58) | PRCPCYP3A4CYP2C9CYP1A2NR1I2 | |
| SCHEMBL2708425 | 0.70 | PRCP (0.51) | PRCPCYP3A4CYP2C9CYP1A2NR1I2 | |
| SCHEMBL205053 | 0.70 | PRCP (0.51) | PRCPCYP3A4CYP2C9CYP1A2NR1I2 | |
| SCHEMBL752316 | 0.70 | MAPK13 (0.41) | PRCPCYP3A4CYP2C9NR1I2ABCB11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-104016971-B | Antiviral compound | PHARMASSET INC. (US) | 2016-05-25 | — | — | CN | disclosed |