Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.37 |
| ▸ | SLC37A4 | O43826 | 1/20 | 0.36 |
| ▸ | RARB | P10826 | 1/20 | 0.36 |
| ▸ | BID | P55957 | 3/20 | 0.36 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 2/20 | 0.36 |
| ▸ | BAK1 | Q16611 | 2/20 | 0.36 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.36 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28856905 | 0.88 | FFAR1 (0.40) | FFAR1HCAR2SLC37A4RARBBID | |
| SCHEMBL27932259 | 0.88 | ALDH1A1 (0.37) | HCAR2EP300LDHALDHBALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL28055643 | 0.86 | FFAR1 (0.39) | FFAR1HCAR2SLC37A4RARBBID | |
| SCHEMBL31147070 | 0.86 | FFAR1 (0.39) | FFAR1HCAR2SLC37A4RARBBID | |
| SCHEMBL5920581 | 0.83 | LDHA (0.45) | FFAR1HCAR2SLC37A4RARBBID | |
| SCHEMBL5588180 | 0.81 | LDHA (0.47) | FFAR1HCAR2SLC37A4RARBBID | |
| SCHEMBL28473054 | 0.81 | FFAR1 (0.43) | FFAR1HCAR2SLC37A4RARBBID | |
| SCHEMBL29180339 | 0.81 | ALDH1A1 (0.38) | HCAR2EP300LDHALDHBGPR35 | |
| SCHEMBL7944628 | 0.81 | BID (0.46) | RARBBIDMCL1BCL2L1BAK1 | |
| SCHEMBL14989169 | 0.79 | FFAR1 (0.42) | FFAR1HCAR2SLC37A4RARBBID |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105461624-B | A kind of method that sulfosalicylic acid collaboration cyclopentadienyl titanium dichloride water mutually efficiently prepares quinoline | 陕西师范大学 | 2018-05-08 | — | — | CN | disclosed |
| CN-105461624-A | Method for efficiently preparing quinoline derivative from titanocene dichloride in cooperation with with sulfo-benzoic acid in water phase | UNIV SHAANXI NORMAL | 2016-04-06 | — | — | CN | disclosed |