Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9261857 | 1.00 | GLRA1 (0.53) | GLRA1POLBMAOAMAOBLMNA | |
| SCHEMBL28078446 | 0.87 | GLRA1 (0.60) | GLRA1POLBMAOBLMNAMAPK1 | |
| SCHEMBL27704828 | 0.87 | HTR1A (0.46) | GLRA1POLBLMNAMAPK1MAPT | |
| SCHEMBL28060116 | 0.85 | GLRA1 (0.50) | GLRA1POLBMAOBLMNAMAPK1 | |
| SCHEMBL28060115 | 0.85 | GLRA1 (0.50) | GLRA1POLBMAOBLMNAMAPK1 | |
| SCHEMBL6035907 | 0.82 | GLRA1 (0.50) | GLRA1MAOAMAOBMAPK1MAPT | |
| SCHEMBL27833449 | 0.80 | TDP1 (0.50) | LMNAMAPK1ALDH1A1MAPTTDP1 | |
| SCHEMBL28060079 | 0.80 | GLRA1 (0.54) | GLRA1POLBMAOBLMNAMAPK1 | |
| SCHEMBL28060089 | 0.80 | GLRA1 (0.54) | GLRA1POLBMAOBLMNAMAPK1 | |
| SCHEMBL26908057 | 0.80 | GLRA1 (0.57) | GLRA1LMNAMAPK1HPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105384608-B | A kind of cumene amphyl and preparation method thereof | 四川海思科制药有限公司 | 2019-08-16 | — | — | CN | disclosed |
| CN-105384608-A | Isopropyl-phenol derivative and preparation method therefor | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2016-03-09 | — | — | CN | disclosed |