Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 2/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16958435 | 0.81 | TSHR (0.42) | LMNATSHRHPGDPOLBALOX15 | |
| SCHEMBL9261857 | 0.80 | GLRA1 (0.53) | GLRA1MAPK1MAPTTDP1L3MBTL1 | |
| SCHEMBL8406366 | 0.78 | HTR1A (0.53) | GLRA1BCHE | |
| SCHEMBL8406586 | 0.78 | GLRA1 (0.51) | GLRA1MAPK1MAPTTDP1L3MBTL1 | |
| SCHEMBL9946104 | 0.78 | IDO1 (0.52) | GLRA1L3MBTL1MAOBTSHRALDH1A1 | |
| SCHEMBL128058 | 0.77 | GLRA1 (0.57) | GLRA1LMNAALDH1A1HPGDFFAR1 | |
| SCHEMBL6035907 | 0.77 | GLRA1 (0.50) | GLRA1MAPK1MAPTTDP1L3MBTL1 | |
| SCHEMBL31419968 | 0.75 | GLRA1 (0.62) | GLRA1MAPTTDP1MAOBLMNA | |
| SCHEMBL14200117 | 0.75 | HTR1A (0.50) | GLRA1MAPK1MAPTLMNAALDH1A1 | |
| SCHEMBL8406368 | 0.75 | LCK (0.46) | GLRA1MAOBBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105384608-B | A kind of cumene amphyl and preparation method thereof | 四川海思科制药有限公司 | 2019-08-16 | — | — | CN | disclosed |
| CN-105384608-A | Isopropyl-phenol derivative and preparation method therefor | SICHUAN HAISCO PHARMACEUTICAL CO LTD | 2016-03-09 | — | — | CN | disclosed |