SCHEMBL28060100

SCHEMBL28060100

COC(=O)c1ccc(Cl)cc1S(=O)(=O)N(C)c1ccccc1

nearest known ligand 0.63

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.63
GPR27 Q9NS67 1/20 0.54
LMNA P02545 4/20 0.47
ALDH1A1 P00352 3/20 0.47
MCOLN3 Q8TDD5 1/20 0.47
ABL1 P00519 1/20 0.47
SMN1; SMN2 Q16637 1/20 0.44
KMT2A Q03164 2/20 0.44
CA1 P00915 1/20 0.43
CA2 P00918 1/20 0.43
CA5A P35218 1/20 0.43
CA9 Q16790 1/20 0.43
PGR P06401 3/20 0.43
MAPT P10636 1/20 0.43
HPGD P15428 1/20 0.43
ACLY P53396 1/20 0.43
MEN1 O00255 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19194087 0.90 KDM4E (0.59) KDM4EGPR27LMNAALDH1A1MCOLN3
SCHEMBL28066164 0.87 KDM4E (0.69) KDM4EGPR27LMNAALDH1A1MCOLN3
SCHEMBL21798567 0.86 KDM4E (0.53) KDM4EGPR27LMNAALDH1A1MCOLN3
SCHEMBL20501209 0.85 ALDH1A1 (0.49) KDM4EGPR27LMNAALDH1A1MCOLN3
SCHEMBL6542414 0.84 CA1 (0.49) KDM4EGPR27LMNAMCOLN3ABL1
SCHEMBL19182003 0.83 ABL1 (0.43) KDM4EGPR27LMNAALDH1A1MCOLN3
SCHEMBL21798595 0.81 KDM4E (0.49) KDM4EGPR27LMNAALDH1A1MCOLN3
SCHEMBL6534758 0.79 KDM4E (0.69) KDM4EALDH1A1MCOLN3KMT2APGR
SCHEMBL8627703 0.78 ABL1 (0.48) KDM4EALDH1A1MCOLN3ABL1SMN1; SMN2
SCHEMBL7683091 0.77 GAA (0.57) KDM4EGPR27LMNAALDH1A1MCOLN3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114507192-A Preparation method of intermediate for preparing tianeptine sodium 上海微巨实业有限公司 2022-05-17 CN claimed
CN-114507192-A Preparation method of intermediate for preparing tianeptine sodium 上海微巨实业有限公司 2022-05-17 CN disclosed
CN-114507192-A Preparation method of intermediate for preparing tianeptine sodium 上海微巨实业有限公司 2022-05-17 CN disclosed
CN-105503668-A Synthetic method of 4-chloro-2-(N-methyl-N-phenyl sulfamoyl) methyl benzoate JINAN CHENGHUI SHUANGDA CHEMICAL CO LTD 2016-04-20 CN disclosed
CN-105503668-A Synthetic method of 4-chloro-2-(N-methyl-N-phenyl sulfamoyl) methyl benzoate JINAN CHENGHUI SHUANGDA CHEMICAL CO LTD 2016-04-20 CN disclosed