SCHEMBL28060104

SCHEMBL28060104

CN(C)c1ccccc1C(=C(c1ccccc1)c1ccccc1)c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.55
MAPT P10636 3/20 0.55
GAA P10253 2/20 0.55
TP53 P04637 1/20 0.55
TSHR P16473 1/20 0.55
SMN1; SMN2 Q16637 1/20 0.55
CNR2 P34972 2/20 0.39
RAB9A P51151 2/20 0.38
KMT2A Q03164 2/20 0.38
HPGD P15428 2/20 0.38
NPC1 O15118 1/20 0.38
MEN1 O00255 1/20 0.38
HSP90AA1 P07900 1/20 0.38
HIF1A Q16665 1/20 0.37
HTR6 P50406 1/20 0.36
GFER P55789 1/20 0.36
KDM4E B2RXH2 3/20 0.35
ESR1 P03372 1/20 0.35
CHEK1 O14757 1/20 0.35
NEK2 P51955 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14922699 0.79 ALDH1A1 (0.43) ALDH1A1MAPTGAATP53TSHR
SCHEMBL12884555 0.78 ALDH1A1 (0.42) ALDH1A1MAPTGAATP53TSHR
SCHEMBL10931124 0.78 ALDH1A1 (0.53) ALDH1A1MAPTGAATP53TSHR
SCHEMBL501813 0.78 MAPT (0.77) ALDH1A1MAPTGAATP53TSHR
SCHEMBL7673917 0.78 ALDH1A1 (0.53) ALDH1A1MAPTGAATP53TSHR
SCHEMBL9126623 0.78 MEN1 (0.55) ALDH1A1MAPTGAATP53TSHR
SCHEMBL6709769 0.78 MAPT (0.36) ALDH1A1MAPTGAATP53TSHR
SCHEMBL4877612 0.78 ALDH1A1 (0.53) ALDH1A1MAPTGAATP53TSHR
SCHEMBL29384309 0.78 MAPT (0.77) ALDH1A1MAPTGAATP53TSHR
SCHEMBL5828459 0.78 ALDH1A1 (0.53) ALDH1A1MAPTGAATP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105473627-B Ion sensor 国立研究开发法人科学技术振兴机构 2017-10-20 CN disclosed
CN-105473627-A Ion sensor JAPAN SCIENCE & TECH AGENCY 2016-04-06 CN disclosed