SCHEMBL6709769

SCHEMBL6709769

c1ccc(C(=C(c2ccccc2)c2ccccc2N(c2ccccc2)c2ccccc2)c2ccccc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.36
ALDH1A1 P00352 3/20 0.36
L3MBTL1 Q9Y468 3/20 0.36
HPGD P15428 3/20 0.36
GAA P10253 2/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
KDM4E B2RXH2 3/20 0.34
CYP3A4 P08684 3/20 0.34
TDP1 Q9NUW8 3/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
PTGS2 P35354 1/20 0.32
AKR1C3 P42330 1/20 0.32
NR4A2 P43354 1/20 0.32
ESR1 P03372 3/20 0.32
SNCA P37840 2/20 0.32
CYP19A1 P11511 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5815520 0.88 NPC1 (0.40) MAPTALDH1A1HPGDGAAMEN1
SCHEMBL28291508 0.80 ALDH1A1 (0.50) MAPTALDH1A1L3MBTL1HPGDGAA
SCHEMBL23471531 0.80 NPC1 (0.38) MAPTALDH1A1HPGDGAAMEN1
SCHEMBL23471523 0.79 TTR (0.37) MAPTALDH1A1HPGDGAAMEN1
SCHEMBL21808781 0.78 AKR1C3 (0.53) MAPTALDH1A1L3MBTL1HPGDGAA
SCHEMBL3972799 0.78 MEN1 (0.44) MAPTALDH1A1L3MBTL1HPGDGAA
SCHEMBL23471530 0.78 ALDH1A1 (0.35) MAPTALDH1A1L3MBTL1HPGDKMT2A
SCHEMBL28060104 0.78 ALDH1A1 (0.55) MAPTALDH1A1HPGDGAAMEN1
SCHEMBL23480332 0.77 ALOX5 (0.35) MAPTMEN1KMT2ACYP2C19SMN1; SMN2
SCHEMBL13515162 0.76 ALDH1A1 (0.52) MAPTALDH1A1L3MBTL1HPGDGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040021136-A1 Luminescent material, luminescent element, and device MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2004-02-05 US disclosed
US-20030143427-A1 Exciton forming substance, luminescent material using the substance, method for light emission and luminescent element, and device using the element MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) 2003-07-31 US disclosed