Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | DAO | P14920 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 3/20 | 0.37 |
| ▸ | PRMT6 | Q96LA8 | 3/20 | 0.37 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
| ▸ | GLS | O94925 | 1/20 | 0.36 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.36 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.36 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16347292 | 0.88 | CHRM2 (0.46) | CHRM2CHRM1CHRM3DAOSCD | |
| SCHEMBL28060157 | 0.78 | CHRM2 (0.45) | CHRM2CHRM1CHRM3DAOCNR1 | |
| SCHEMBL5537502 | 0.73 | CHRM2 (0.62) | CHRM2CHRM1CHRM3DAOCNR1 | |
| SCHEMBL1035570 | 0.71 | CHRM2 (0.58) | CHRM2CHRM1CHRM3DAOCNR1 | |
| SCHEMBL1047406 | 0.71 | CHRM2 (0.58) | CHRM2CHRM1CHRM3DAOCNR1 | |
| SCHEMBL2090446 | 0.71 | CHRM2 (0.59) | CHRM2CHRM1CHRM3DAOCNR1 | |
| SCHEMBL29394922 | 0.70 | PIM1 (0.52) | CHRM2CHRM1CHRM3 | |
| SCHEMBL68710 | 0.70 | PIM1 (0.52) | CHRM2CHRM1CHRM3 | |
| SCHEMBL31395106 | 0.70 | MRGPRX4 (0.56) | CHRM2CHRM1CHRM3CYP19A1CYP11B1 | |
| SCHEMBL5543404 | 0.70 | CHRM2 (0.58) | CHRM2CHRM1CHRM3DAOCNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105492429-A | Heteroaryl inhibitors of SUMO activating enzyme | MILLENNIUM PHARM INC | 2016-04-13 | — | — | CN | disclosed |