Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.45 |
| ▸ | GLS | O94925 | 2/20 | 0.44 |
| ▸ | SCD | O00767 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | DAO | P14920 | 1/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.39 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.39 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28060132 | 0.78 | CHRM2 (0.50) | CHRM2CHRM1CHRM3GLSSCD | |
| SCHEMBL1714299 | 0.74 | CYP3A4 (0.58) | GLS | |
| SCHEMBL27643005 | 0.74 | CHRM2 (0.53) | CHRM2CHRM1CHRM3GLSCNR1 | |
| SCHEMBL5181367 | 0.73 | CHRM2 (0.56) | CHRM2CHRM1CHRM3CNR1DAO | |
| SCHEMBL29103739 | 0.71 | ALDH1A1 (0.53) | CHRM2CHRM1CHRM3CYP19A1CYP11B1 | |
| SCHEMBL27997591 | 0.70 | CHRM2 (0.55) | CHRM2CHRM1CHRM3CNR1DAO | |
| SCHEMBL11546048 | 0.70 | CHRM2 (0.51) | CHRM2CHRM1CHRM3GLSCNR1 | |
| SCHEMBL16347284 | 0.70 | SCD (0.52) | CHRM3GLSSCDCYP19A1CYP11B1 | |
| SCHEMBL1271844 | 0.69 | FFAR1 (0.67) | CHRM2CHRM1CHRM3CNR1DAO | |
| SCHEMBL6205346 | 0.69 | CHRM2 (0.53) | CHRM2CHRM1CHRM3CNR1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105492429-A | Heteroaryl inhibitors of SUMO activating enzyme | MILLENNIUM PHARM INC | 2016-04-13 | — | — | CN | disclosed |