Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN4A | P35499 | 10/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.53 |
| ▸ | THPO | P40225 | 1/20 | 0.53 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.52 |
| ▸ | MAOA | P21397 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | SCN1A | P35498 | 2/20 | 0.52 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.52 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.52 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.52 |
| ▸ | GBA1 | P04062 | 1/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.52 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9201474 | 0.82 | SCN4A (0.55) | SCN4ACYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL104735 | 0.77 | SCN4A (0.48) | SCN4ACYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL6273156 | 0.76 | SCN4A (0.47) | SCN4ACYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL11580891 | 0.74 | SCN4A (0.45) | SCN4ACYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL6274601 | 0.74 | SCN4A (0.52) | SCN4ACYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL9198060 | 0.74 | SCN4A (0.53) | SCN4ACYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL23880668 | 0.73 | SCN4A (0.45) | SCN4ACYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL23804880 | 0.73 | SCN4A (0.45) | SCN4ACYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL11745605 | 0.73 | SCN4A (0.45) | SCN4ACYP1A2CYP3A4CYP2D6NFKB1 | |
| SCHEMBL515979 | 0.73 | SCN4A (0.45) | SCN4ACYP1A2CYP3A4CYP2D6NFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105473574-B | Somatostatin receptor subtype 4(SSTR4) agonists | 森特克森治疗公司 | 2018-02-13 | — | — | CN | disclosed |
| CN-105473574-A | Novel somatostatin receptor subtype 4(SSTR4) agonists | BOEHRINGER INGELHEIM INT | 2016-04-06 | — | — | CN | disclosed |