SCHEMBL104735

SCHEMBL104735

Cc1cccc(C)c1OC(C)C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SCN4A P35499 9/20 0.48
CYP1A2 P05177 3/20 0.48
LMNA P02545 2/20 0.48
SCN1A P35498 2/20 0.48
SCN5A Q14524 2/20 0.48
SCN9A Q15858 2/20 0.48
CYP3A4 P08684 2/20 0.48
CYP2D6 P10635 2/20 0.48
NFKB1 P19838 2/20 0.48
TSHR P16473 2/20 0.48
CYP2C9 P11712 1/20 0.48
KCNK3 O14649 1/20 0.48
CACNA1F O60840 1/20 0.48
KCNK2 O95069 1/20 0.48
GBA1 P04062 1/20 0.48
MAOA P21397 1/20 0.48
HTR2A P28223 1/20 0.48
SLC6A4 P31645 1/20 0.48
HTR2B P41595 1/20 0.48
SCN7A Q01118 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16606241 0.86 SCN4A (0.42) SCN4ACYP1A2LMNASCN1ASCN5A
SCHEMBL16572835 0.84 KDM4E (0.45) SCN4ACYP1A2LMNASCN1ASCN5A
SCHEMBL12440951 0.84 ALDH1A1 (0.44) SCN4ACYP1A2LMNASCN1ASCN5A
SCHEMBL9945947 0.84 LMNA (0.41) SCN4ACYP1A2LMNASCN1ASCN5A
SCHEMBL14409292 0.84 ACHE (0.44) SCN4ACYP1A2LMNASCN1ASCN5A
SCHEMBL15183452 0.84 TRPA1 (0.46) SCN4ACYP1A2LMNASCN1ASCN5A
SCHEMBL29581599 0.83 SCN4A (0.37) SCN4ACYP1A2LMNASCN1ASCN5A
SCHEMBL27387343 0.83 SCN4A (0.37) SCN4ACYP1A2LMNASCN1ASCN5A
SCHEMBL3718003 0.83 SCN4A (0.44) SCN4ACYP1A2LMNASCN1ASCN5A
SCHEMBL25742996 0.82 SCN4A (0.37) SCN4ACYP1A2LMNASCN1ASCN5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240026053-A1 TRANSPARENT ARTICLE POLYPLASTICS CO., LTD. (JP) 2024-01-25 US disclosed
US-11877506-B2 Polycyclic aromatic compound KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) 2024-01-16 US disclosed
US-20210340320-A1 Oligomer (2,6-dimethylphenylene ether) Together with Fabrication Method and Cured Product Thereof CPC CORPORATION, TAIWAN (TW) 2021-11-04 US disclosed
CN-112074506-A 4' -halo-containing nucleotide and nucleoside therapeutic compositions and uses related thereto 埃默里大学 2020-12-11 CN disclosed
EP-3359585-B1 USE OF COMPOUNDS IN POLYMERISATION REACTIONS SCG CHEMICALS CO LTD (TH) 2019-07-24 EP disclosed
US-20170196862-A2 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR VERTEX PHARMACEUTICALS INCORPORATED (US) 2017-07-13 US disclosed
CN-104334525-B catechol O-methyltransferase activity inhibiting compounds 奥赖恩公司 2017-05-10 CN disclosed
WO-2017060691-A1 USE OF COMPOUNDS IN POLYMERISATION REACTIONS SCG CHEMICALS CO., LTD. (TH) 2017-04-13 WO disclosed
US-9365588-B2 Benzoxazines as modulators of ion channels VERTEX PHARMACEUTICALS INCORPORATED (US) 2016-06-14 US disclosed
CN-104334525-A Catechol o-methyltransferase activity inhibiting compounds ORION CORP 2015-02-04 CN disclosed
US-20090184631-A1 Novel red electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-07-23 US disclosed
US-20090179555-A1 Novel red electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-07-16 US disclosed
US-20090179555-A1 Novel red electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-07-16 US disclosed
US-20090174316-A1 Novel red electroluminescent compounds and organi electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-07-09 US disclosed
US-20090174316-A1 Novel red electroluminescent compounds and organi electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-07-09 US disclosed
US-20090165860-A1 Electroluminescent device using electroluminescent compounds GRACEL DISPLAY INC. (KR) 2009-07-02 US disclosed
US-20090159130-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-06-25 US disclosed
US-20090153037-A1 Novel red electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-06-18 US disclosed
US-20090145483-A1 Novel electroluminescent compounds and organic electroluminescent device suing the same GRACEL DISPLAY INC. (KR) 2009-06-11 US disclosed
US-20090078317-A1 Organometalic compounds for electroluminescence and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2009-03-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11877506-B2 Polycyclic aromatic compound F11, C1R, RNF31 SCN4A 2579/4885CYP1A2 133/4885LMNA 692/4885
US-20090145483-A1 Novel electroluminescent compounds and organic electroluminescent device suing the same LEF1, ODC1, AOC2 SCN4A 3046/4885CYP1A2 1920/4885LMNA 3749/4885
US-20090078317-A1 Organometalic compounds for electroluminescence and organic electroluminescent device using the same OCIAD1, L1CAM, OCIAD2 SCN4A 2870/4885CYP1A2 1002/4885LMNA 1976/4885
US-20090184631-A1 Novel red electroluminescent compounds and organic electroluminescent device using the same ALDH1A2, ODC1, NDUFS2 SCN4A 2157/4885CYP1A2 697/4885LMNA 3971/4885
US-20090174316-A1 Novel red electroluminescent compounds and organi electroluminescent device using the same ALPI, IK, ALDH1A2 SCN4A 3331/4885CYP1A2 2596/4885LMNA 4437/4885
US-20090153037-A1 Novel red electroluminescent compounds and organic electroluminescent device using the same NDUFS2, ALDH1A2, ODC1 SCN4A 2225/4885CYP1A2 723/4885LMNA 3962/4885
US-20090159130-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same AOX1, LEF1, ODC1 SCN4A 2210/4885CYP1A2 750/4885LMNA 4071/4885
US-20090179555-A1 Novel red electroluminescent compounds and organic electroluminescent device using the same NDUFS2, ALDH1A2, ODC1 SCN4A 2225/4885CYP1A2 723/4885LMNA 3962/4885
US-20170196862-A2 MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR CFTR, SCNN1B, SLC26A4 SCN4A 79/4885CYP1A2 3773/4885LMNA 3018/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.