Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA1 | P00915 | 3/20 | 0.48 |
| ▸ | CA2 | P00918 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.47 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | FPR2 | P25090 | 1/20 | 0.41 |
| ▸ | TPMT | P51580 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9566474 | 0.87 | SMN1; SMN2 (0.46) | CA12CA1CA2CA9EPHX2 | |
| SCHEMBL19707415 | 0.80 | CA12 (0.68) | CA12CA1CA2CA9CNR1 | |
| SCHEMBL2090693 | 0.78 | CA1 (0.50) | CA12CA1CA2CA9CNR1 | |
| SCHEMBL1092529 | 0.78 | CA12 (0.50) | CA12CA1CA2CA9CNR1 | |
| SCHEMBL2891738 | 0.78 | MAPT (0.60) | CA12CA1CA2CA9EPHX1 | |
| SCHEMBL23752220 | 0.76 | CA12 (0.48) | CA12CA1CA2CA9CNR1 | |
| SCHEMBL669782 | 0.76 | SMN1; SMN2 (0.67) | CA12CA1CA2CA9 | |
| SCHEMBL5533070 | 0.76 | PEPD (0.64) | CA12CA1CA2CA9TRPV1 | |
| SCHEMBL2085466 | 0.76 | ALDH1A1 (0.61) | CA12CA1CA2CA9 | |
| SCHEMBL9835553 | 0.76 | CA12 (0.48) | CA12CA1CA2CA9CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105384739-A | Pyrazolo[3,4-c]pyridine derivative | CSPC ZHONGQI PHARMACEUTICAL TECH (SHIJIAZHUANG) CO LTD | 2016-03-09 | — | — | CN | disclosed |